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Protein Biochemistry
Chemicals and Reagents
GC7 Sulfate
GC7 Sulfate from MedChemExpress
Be the first to write a review!
Citations:
(8)
Supplier Page
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MedChemExpress for
GC7 Sulfate
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Description
GC7 Sulfate is a
deoxyhypusine synthase
(
DHPS
) inhibitor
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
GC7 Sulfate
Company
MedChemExpress
Price
$66.00
Supplier Page
View Company Product Page
Catalog Number
HY-108314A
Quantity
10 mM * 1 mL
Applications
Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity
98.0%
Type
Chemical
Molecular Weight
270.35
Molecule Name
GC7 Sulfate
Formula
C8H22N4O4S
Research Area
Cancer
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MedChemExpress
1 Deer Park Drive, Suite F
MONMOUTH JUNCTION
,
NJ
08852
United States
Phone
: US Tel: 609-228-6898
US Fax: 609-228-5909
EU Tel: +4686500910
Email: sales@medchemexpress.com
eu.sales@MedChemExpress.com
Company Profile
Website:
medchemexpress.com
Citations (8)
(1)
SNOR promotes translation restart after dormancy
Nature
May 13, 2026
Maciej Gluc, Higor Rosa, Maria Bozko, Lesley A. Turner, Cassidy R. Prince, Yelena Peskova, Heather A. Feaga, Kathleen L. Gould, Simone Mattei, Ahmad Jomaa
(w/v) glucose, with or without 20 µM
GC7 sulfate
(deoxyhypusine synthase
inhibitor
;
MedChemExpress
,
HY-108314A
). This time point was designated day 0 of the experiment, and cultures were maintained at 30 °C for
(2)
Uncovering cancer dependencies in peptide-interacting protein pockets
bioRxiv
March 25, 2026
Mihkel Örd, Liz Kogan, Devin Bradburn, Michelle Leiser, Mardo Kõivomägi, Norman E. Davey, Pau Creixell
Sigma-Aldrich
) was dissolved at 1 mg/ml in DMSO.
Nutlin-3a
(
S8059
,
Selleck
) was dissolved at 5 mM in DMSO. GC7 (
HY-108314A
,
MedChemExpress
) was dissolved at 10 mM in H2O.
PCLX-001
(T63788, Cambridge Bioscience) was dissolved
(3)
Spermine attenuates TGF-β-induced EMT by downregulating fibronectin
Journal of Biological Chemistry
April 1, 2025
Huidong Liu, Ye-Guang Chen
anti-rabbit IgG (Jackson; cataog no.: 711-605-152). The following compounds were used: GC7 (
MCE
; catalog no.:
HY-108314A
), putrescine (Macklin; catalog no.: D806929), spermidine (Sigma; catalog no.: 85578), spermine (Sigma;
(4)
Probiotics and their metabolite spermidine enhance IFN-γ(+)CD4(+) T cell immunity to inhibit hepatitis B virus
Cell reports. Medicine
November 19, 2024
Wang T, Fan Y, Tan S, Wang Z, Li M, Guo X, Yu X, Lin Q, Song X, Xu L,
et al
.
peptide,
AnaSpec
,Cat#
AS-27024
Spermidine
,
Sigma
,Cat# S0266-5G 3-Methyladenine(3-MA),
MCE
,Cat#
HY-19312
GC-7,
MCE
,Cat#
HY-108314A
Entecavir
,
MCE
,Cat#
HY-13623A
,, Critical commercial
assays
,Critical commercial
assays
,Critical commercial
(5)
Polyamine-mediated ferroptosis amplification acts as a targetable vulnerability in cancer
Nat Commun
March 19, 2024
Guoshu Bi, Jiaqi Liang, Yunyi Bian, Guangyao Shan, Yiwei Huang, Tao Lu, Huan Zhang, Xing Jin, Zhencong Chen, Mengnan Zhao,
et al.
compounds were obtained from
MedChemExpress
(
MCE
, USA):
AMXT-1501
(
HY-124617A
), DFMO (
HY-B0744
), GC7 (
HY-108314A
). The following compounds were obtained from Sangon Biotech (China): l-arginine (A600205), l-citrulline
(6)
Bracovirus Sneaks Into Apoptotic Bodies Transmitting Immunosuppressive Signaling Driven by Integration-Mediated eIF5A Hypusination
Frontiers in immunology
January 1, 2022
Zhou GF, Chen CX, Cai QC, Yan X, Peng NN, Li XC, Cui JH, Han YF, Zhang Q, Meng JH,
et al
.
further studies. Methods Details Reagents DHYS
inhibitor
GC7 was purchased from MedChemExpress (
HY-108314A
,
MCE
). Apoptosis Analysis Analysis of apoptotic
hemocytes
was performed using an
Annexin V-FITC/PI apoptosis detection kit
(7)
Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients
Cellular oncology (Dordrecht)
December 1, 2014
Bandino A, Geerts D, Koster J, Bachmann AS.
(8)
N1-guanyl-1,7-diaminoheptane (GC7) enhances the therapeutic efficacy of doxorubicin by inhibiting activation of eukaryotic translation initiation factor 5A2 (eIF5A2) and preventing the epithelial-mesenchymal transition in hepatocellular carcinoma cells
Experimental cell research
October 15, 2013
Lou B, Fan J, Wang K, Chen W, Zhou X, Zhang J, Lin S, Lv F, Chen Y.
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GC7 Sulfate from MedChemExpress
Supplier Page
View Company Product Page
$66.00
Product Specs
Company Info
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