Description
A pyrrole with diverse biological activities; active against C. albicans, C. neoformans, B. dermatitidis, S. schenckii, and H. capsulatum isolates (MICs = S. antibioticus, B. subtilis, and S. aureus (MICs = 0.2, 6.25, and 12.5 µg/ml, respectively); reduces spore germination, germ-tube length, and sporulation in B. cinerea isolates (EC50s = 2.3-31.8 µg/L); reduces C. albicans levels by 74% in the kidney of infected mice at 50 mg/kg