Description
FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9 (IC50: 5.8uM;CDK9/cyclin T1).FIT-039 inhibits replication of HSV-1 (IC50 of 0.69uM), HSV-2,human adenovirus, and human CMV.FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses