Description
Revaprazan (SB-641257; YH-1885) is a potent potassium-competitive acid blocker (P-CAB) that inhibits H+, K+-ATPase in a reversible and K+-competitive manner; reduces gastric acid secretion, also exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. UlcerApproved