Description
PI-083 is a platelet aggregation inhibitor produced by Streptomyces matensis A-6621. It is active against gram-positive bacteria with MIC of 0.39-3.13 µg/mL. It inhibits platelet aggregation induced by ADP, Arachidonic Acid and collagen with MIC of 30.4, 1.9 and 3.8 µmol/L. It also inhibits KB cell growth with IC50 of 0.026 µmol/L