Description
A coumarin glucoside; inhibits A23187-induced production of PGE2 and LTC4 in isolated mouse peritoneal macrophages at 100 µM; reduces synovial inflammation and fibrosis, as well as bone and cartilage erosion, in the inflamed joints in a complete Freund’s adjuvant- and M. butyricum-induced rat model of rheumatoid arthritis at 50 and 100 mg/kg