Description
An anxiolytic agent; selectively binds to α1β2γ2 subunit-containing GABAA receptors over α5β2γ2 subunit-containing receptors in HEK293 cells (IC50s = 0.017 and ≥10 µM, respectively, for the recombinant rat receptors); binds to the GABAA/benzodiazepine receptor complex and TSPO (IC50s = 0.028 and 0.0079 µM, respectively); reduces marble burying in mice (MED = 10 mg/kg)