Description
A PI4KIIIα inhibitor (IC50 = 3.16 nM); selective for PI4KIIIα over PI4KIIIβ, PI3Kα, PI3Kβ, and PI3Kδ (IC50s = >50 nM); inhibits PI3Kγ (IC50 = 15.8 nM); decreases the levels of PtdIns-(4)-P1 in HEK293 cells expressing the AT1 receptor (IC50 = 3 nM); inhibits HCV genotype 1a and 1b replication