Description
A cephalosporin antibiotic; inhibits the growth of both Gram-positive and Gram-negative bacteria; inhibits the growth of E. coli, E. faecalis, E. faecium, N. gonorrhoeae, N. meningitidis, P. mirabilis, S. aureus, S. pyogenes, and S. pneumoniae strains (MICs = 0.013-25 µg/ml) and clinical isolates of penicillin-susceptible, -intermediate, and -resistant S. pneumoniae and methicillin-sensitive S. aureus (MIC90s = 0.12-16 µg/ml); protects mice challenged with E. coli, S. aureus, S. pyogenes, and P. mirabilis strains (PD50s = 0.07-1.3 mg/kg)