Description
A muscarinic antagonist and β2-adrenergic receptor (β2-AR) agonist (Kis = 1.4, 1.3, and 3.7 nM, for hM2, hM3, and hβ2-AR, respectively); exhibits potent hβ2-AR agonist activity (EC50 = 0.29 nM) with 440- and 320-fold selectivity over hβ1- and hβ3-ARs, respectively; induces smooth muscle relaxation; inhibits bronchoconstrictor response