Description
An NSAID and COX-1 inhibitor (IC50 = 20 nM); selective for COX-1 over COX-2 (IC50 = 322 nM); inhibits arachidonic acid-induced platelet aggregation in washed isolated human platelets (IC50 = 0.16 µM); reduces paw thickness in a rat model of carrageenan-induced paw edema when applied topically as a nanogel in SLNs