Ophiobolin C from Cayman Chemical

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Cayman Chemical for
Ophiobolin C

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Description

A phytoxin that antagonizes chemokine receptor CCR5 binding (IC50 = 40 µM) to the envelope protein gp120 and to CD4, which is known to mediate HIV-1 viral entry into cells; cytotoxic to CLL cells (LC50 = 8 nM)