Description
An antibiotic and derivative of tunicamycin; active against B. subtilis (MIC = 0.3 µg/ml); increases the efficacy of the β-lactam antibiotics oxacillin, methicillin, and penicillin G against B. subtilis at 0.4 µg/ml; unlike tunicamycin, it is non-toxic to S. cerevisiae (MIC = >10 µg/ml) and does not inhibit glycosylation in a protein N-glycosylation assay; has reduced antiproliferative activity against MDA-MB-231 and CHO cells compared with tunicamycin