Description
A selective inhibitor of Epac2 (IC50 = 300 nM); inhibits Epac2 guanine nucleotide exchange activity; does not inhibit Epac1-mediated Rap1-GDP exchange activity or cAMP-mediated PKA activation in vitro; blocks stimulation of Epac2, but not Epac1, by 007-AM in HEK293 cells