Description
MC70 is a potent and selective modulator of P-glycoprotein(P-gp) with EC50 value of 0.69 µM. It is also an inhibitor of the ABC transporter ABCB1 (aka MDR1). It potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. It is potential to be used as novel anticancer agent with both cytostatic and cytotoxic characteristics