GSK484, PAD4 inhibitor from Abcam

Product Specs
ItemGSK484, PAD4 inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab223598
Quantity1 mg
TypeInhibitor, inhibitor
Molecule NameGSK484

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Tunable Self-Assembling Cellular Microarray for Single-Neutrophil Vital and Suicidal Extracellular TrapsLab on a ChipJuly 6, 2026Jacob Doon-Ralls, Sophia Mayone, Xilal Y. Rima, Dharti Shantaram, Kim Truc Nguyen, Ajeet Singh, Bradley J. Needleman, Sabrena Noria, Stacy Brethauer, Kyle A. Perry, et al.488-conjugated anti-MLKL (phosphor S358, 1 : 100 dilution, Abcam Cat# ab187091), 10 μM GSK484 (Abcam Cat# ab223598) and/or 1 μm SYTOX Orange™, then the wells were sealed with a 12 mm round coverslip. What was included

(2) Oxidation of hemoglobin to ferryl hemoglobin contributes to remodeling of the artery wall in abdominal aortic aneurysmRedox BiologyDecember 1, 2025Yuchao Ding, László Potor, Éva Katona, Péter Sótonyi, Ágnes Szappanos, Gergő Péter Gyurok, Gábor Méhes, Zoltán Hendrik, Attila Fintha, Péter Attila Gergely, et al.μmol/l Hb for a total of 16 h. Human neutrophils were treated with 5 μmol/l ferrylHb or 5 μmol/l GSK484 (ab223598, Abcam) for 16 h. 2.19 Polymorphonuclear leukocyte elastase assay Polymorphonuclear leukocyte (PMN)

(3) Targeted citrullination enables p53 binding to non-canonical sitesMolecular CellOctober 2, 2025Alexandra Indeglia, Andrea Valdespino, Giulia Pantella, Sarah Offley, Connor Hill, Maya Foster, Kaitlyn Casey, Hsin-Yao Tang, Anneliese M. Faustino, Alessandro Gardini, et al.NaCl at 37°C for 1 hour. Samples were also incubated with an inhibitor against PADI4 (GSK484, Abcam # ab223598). As a positive control, 125 ng of recombinant mononucleosomes (Active Motif #81070) were also incubated

(4) The PAD4 inhibitor GSK484 diminishes neutrophil extracellular trap in the colon mucosa but fails to improve inflammatory biomarkers in experimental colitisBioscience ReportsJune 27, 2025Kangzhe Xie, Jordan Hunter, Aaron Lee, Gulfam Ahmad, Paul K. Witting, Tamara Ortiz-Cerdawhilst PAD4 inhibitor, GSK484, was acquired from a commercial source (Abcam, Sydney Australia, Cat# ab223598; purity > 98%). The doses and administration routes for MPO and PAD4 inhibitors were selected based

(5) hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50Molecular CellFebruary 1, 2024Vasty Osei-Amponsa, Monika Chandravanshi, Xiuxiu Lu, Valentin Magidson, Sudipto Das, Thorkell Andresson, Marzena Dyba, Venkata R. Sabbasani, Rolf E. Swenson, Caroline Fromont, et al.,Selleck Chemicals LLC,Cat#S8044 PAD CI-amidine,Sigma,Cat#506282 GSK484 (PADI4 specific inhibitor),Abcam,Cat#ab223598 GSK484 (PADI4 specific inhibitor),Cayman Chemical Co Inc,Cat#17488 Lipofectamine™ 3000 Reagent,Thermo Fisher Scientific

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GSK484, PAD4 inhibitor from Abcam

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GSK484, PAD4 inhibitor from Abcam

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