TP 064 from Tocris Bioscience, a Bio-Techne Brand | Biocompare.com

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TP 064

Potent and selective PRMT 4 inhibitor

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Tocris Bioscience, a Bio-Techne Brand for
TP 064

Description

Potent and selective PRMT 4 inhibitor

Product Specs
ItemTP 064
CompanyTocris Bioscience, a Bio-Techne Brand
Price $191.00Supplier Page View Company Product Page
Catalog Number6008/10
Quantity10 mg (also 50 mg)
Purity98%
Molecular Weight458.6
Molecule NameN-Methyl-N-((2-(1-(2-(methylamino)ethyl)piperidin-4-yl)pyridin-4-yl)methyl)-3-phenoxybenzamide
FormulaC28H34N4O2
StorageStore at -20°C

Specifications/Features

Sizes Available: 10 mg (also 50 mg)

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Protein arginine methyltransferase 4 modulates nitric oxide synthase uncoupling and cerebral blood flow in Alzheimer's diseaseJournal of cellular physiologyJune 1, 2024Clemons GA, Silva ACE, Acosta CH, Udo MSB, Tesic V, Rodgers KM, Wu CY, Citadin CT, Lee RH, Neumann JT, et al.

(2) Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsisThoraxApril 1, 2023Lai Y, Li X, Li T, Li X, Nyunoya T, Chen K, Kitsios G, Nouraie M, Zhang Y, McVerry BJ, et al.

(3) Arginine methylation of BRD4 by PRMT2/4 governs transcription and DNA repairScience advancesDecember 9, 2022Liu L, Lin B, Yin S, Ball LE, Delaney JR, Long DT, Gan W.

(4) Pan-methylarginine antibody generation using PEG linked GAR motifs as antigensMethods (San Diego, Calif.)April 1, 2022Wang Y, Person MD, Bedford MT.

(5) PRMT4 inhibitor TP-064 inhibits the pro-inflammatory macrophage lipopolysaccharide response in vitro and ex vivo and induces peritonitis-associated neutrophilia in vivoBiochimica et biophysica acta. Molecular basis of diseaseNovember 1, 2021Zhang Y, de Boer M, van der Wel EJ, Van Eck M, Hoekstra M.

(6) Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epitheliaCell death & diseaseSeptember 3, 2021Lai Y, Li X, Li T, Nyunoya T, Chen K, Kitsios GD, Nouraie SM, Zhang Y, McVerry BJ, Lee JS, et al.

(7) CARM1 regulates replication fork speed and stress response by stimulating PARP1Molecular cellFebruary 18, 2021Genois MM, Gagné JP, Yasuhara T, Jackson J, Saxena S, Langelier MF, Ahel I, Bedford MT, Pascal JM, Vindigni A, et al.

(8) CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver CancerCell reportsSeptember 18, 2018Zhong XY, Yuan XM, Xu YY, Yin M, Yan WW, Zou SW, Wei LM, Lu HJ, Wang YP, Lei QY.

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