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Cloning and Expression
Cell Culture / Tissue Culture
Primary Cells, Cell Lines and Microorganisms
Cells and Microorganisms
C4
C4 from ATCC
Be the first to write a review!
Citations:
(6)
Supplier Page
Supplier Page from
ATCC for
C4
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Product Specs
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Citations
Reviews
Product Specs
Item
C4
Company
ATCC
Price
Supplier Page
View Company Product Page
Catalog Number
CRL-3313
Species
Homo sapiens
Type
Cell Biology
Disease
Prostate Cancer
Tissue
Prostate
Volume
1.0 mL
Applications
Property of this cell line: Secretion of prostate specific antigen to culture medium. Applications: Prostate cancer tumorigenicity, androgen-independent progression, and bone metastasis
Quantity
Approximately 1.0 to 2.0 x 10^6
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ATCC
10801 University Boulevard
Manassas
,
Virginia
20110-2209
United States
Phone
: (703) 365-2700
Fax: (703) 365-2701
Company Profile
Website:
http://www.atcc.org
Citations (6)
(1)
Targeting Tumor Microenvironment–Derived NRG1-HER2/3 Signaling with Zenocutuzumab Restores Sensitivity to AR Inhibition in PTEN Wild-type Prostate Cancer
Molecular Cancer Therapeutics
December 30, 2025
Brian M. Shinder, Young Sun Lee, Ninghui Mao, Nazifa Salsabeel, Zeda Zhang, Harmanpreet Kaur, Xiaoping Chen, Qing Chang, Elisa de Stanchina, Anuradha Gopalan,
et al.
July 2024 prior to freezing for banking (18). LNCaP (
ATCC
®
CRL-1740
™, RRID:CVCL_0395) and LAPC4 (
ATCC
®
CRL-3313
™, RRID:CVCL_4744) were purchased from ATCC in 2023 and 2025, respectively. Authentication at ATCC was
(2)
Targeting Tumor Microenvironment–Derived NRG1-HER2/3 Signaling with Zenocutuzumab Restores Sensitivity to AR Inhibition in PTEN Wild-type Prostate Cancer
Mol Cancer Ther
December 10, 2025
Brian M. Shinder, Young Sun Lee, Ninghui Mao, Nazifa Salsabeel, Zeda Zhang, Harmanpreet Kaur, Xiaoping Chen, Qing Chang, Elisa de Stanchina, Anuradha Gopalan,
et al.
recently in July 2024, prior to freezing for banking (18). LNCaP (
CRL-1740
, RRID:CVCL_0395) and LAPC4 (
CRL-3313
, RRID:CVCL_4744) were purchased from the
ATCC
in 2023 and 2025, respectively. Authentication at the
(3)
The Oncometabolite 2-Hydroxyglutarate Is Upregulated in Post-Prostatectomy PSA Recurrence of Prostate Cancer: A Metabolomic Analysis
Molecules
August 8, 2025
Dontrel W. Spencer Hairston, Shamira Sridharan-Weaver, Abheek Gandhi, Neelu Batra, Blythe P. Durbin-Johnson, Marc A. Dall’Era, Paramita M. Ghosh
analysis.
Cell Culture
and Materials.
Human
prostate cancer
cell lines
LNCaP clone FGC
(
CRL-1740
) and C4 (
CRL-3313
) (
ATCC
, Manassas, VA, USA) were cultured in
RPMI 1640 medium
with 5% fetal bovine serum (Gemini Biologicals,
(4)
SHOX2 promotes prostate cancer proliferation and metastasis through disruption of the Hippo-YAP pathway
iScience
September 15, 2023
Wenjie Yang, Hualin Chen, Lin Ma, Jie Dong, Mengchao Wei, Xiaoqiang Xue, Yingjie Li, Zhaoheng Jin, Weifeng Xu, Zhigang Ji
lines,
Experimental models
: Cell lines,
Experimental models
: Cell lines ,,
PC-3
,
ATCC
,
CRL-1435
LNCaP,
ATCC
,
CRL-3313
C4-2B
,
ATCC
,
CRL-3315
VCaP
,
ATCC
,
CRL-2876
MDA PCa 2b
,
ATCC
,
CRL-2422
RWPE-1
,
ATCC
,
CRL-11609
HEK293T,
ATCC
,
CRL-11268
,,
Experimental models
(5)
δ-Tocotrienol is the most potent vitamin E form in inhibiting prostate cancer cell growth and inhibits prostate carcinogenesis in Ptenp−/− mice
Cancer Prev Res (Phila)
April 1, 2022
Hong Wang, William Yan, Yuhai Sun, Chung S. Yang
(
ATCC
Cat#
HTB-81
, RRID:CVCL_0105),
22Rv1
(
ATCC
Cat#
CRL-2505
, RRID:CVCL_1045), and LNCaP (
ATCC
Cat#
CRL-3313
, RRID:CVCL_4783), were obtained from ATCC (Manassas, VA, USA). The
human
cell lines used were less than
(6)
δ-Tocotrienol is the Most Potent Vitamin E Form in Inhibiting Prostate Cancer Cell Growth and Inhibits Prostate Carcinogenesis in Ptenp−/− Mice
Cancer Prevention Research
April 1, 2022
Hong Wang, William Yan, Yuhai Sun, Chung S. Yang
(
ATCC
Cat#
HTB-81
, RRID:CVCL_0105),
22Rv1
(
ATCC
Cat#
CRL-2505
, RRID:CVCL_1045), and LNCaP (
ATCC
Cat#
CRL-3313
, RRID:CVCL_4783), were obtained from ATCC (Manassas, VA, USA). The
human
cell lines used were less than
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C4 from ATCC
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