BEAS-2B from ATCC

Product Specs
ItemBEAS-2B
CompanyATCC
Price Supplier Page View Company Product Page
Catalog NumberCRL-3588
ApplicationsThis cell line is a suitable transfection host. The cells retain the ability to undergo squamous differentiation in response to serum, and can be used to screen chemical and biological agents for ability to induce or affect differentiation and/or carcinogenesis
SpeciesHomo sapiens
TypeCell Biology
Volume1.0 mL
Cell Typeepithelial cell
DiseaseNormal
TissueBronchus, Lung

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ATCC

10801 University Boulevard

Manassas, Virginia 20110-2209

United States

Phone: (703) 365-2700
Fax: (703) 365-2701

Company Profile

Website: http://www.atcc.org

(1) Two Shorter Variants of the Proline-Rich Antimicrobial Peptide B7-005 Scaffold Active Against Clinical Isolates of Pseudomonas aeruginosa and Staphylococcus aureusAntibiotics (Basel)April 18, 2026Giacomo Cappella, Adriana Di Stasi, Clelia Cortese, Luisa Torrini, Agnese D'Amore, Virginia Niccolini, Luigi de Pascale, Bruno Casciaro, Mario Mardirossian, Alessandro Pini, et al.3). 4.5. Cytotoxicity Assay BEAS-2B cells were obtained from the American Type Culture Collection (ATCC® CRL-3588™, Manassas, VA, USA). Cells were maintained as adherent cultures in complete RPMI medium (EuroClone,

(2) Atmospheric particulate matter impairs pulmonary barriers by triggering FTH1-mediated ferroptosisiScienceApril 17, 2026Huiyu Yue, Jing Wang, Ya Li, Haoran Dong, Yangzi Dong, Tiantian Liu, Jiansheng Liwere collected for later experimental detection. Cell lines Human epithelial BEAS-2B cells (ATCC, CRL-3588) were cultured in Dulbecco’s Modified Eagle Medium (DMEM) supplemented with 10% fetal bovine serum (FBS,

(3) 2-Phenylquinolines Exhibit Anti-Severe Acute Respiratory Syndrome Coronavirus-2 Activity Through the Nonstructural Protein 13 Helicase InhibitionChemMedChemApril 14, 2026Giada Cernicchi, Maria Giulia Nizi, Roberta Emmolo, Leentje Persoons, Manon Laporte, Dirk Jochmans, Isabella Romeo, Giacomo Pepe, Ciro Milite, Pietro Campiglia, et al.cytotoxic profile of compounds 14 and 15 was evaluated on human bronchial epithelial cells (BEAS‐2B, ATCC CRL‐3588) and rat cardiomyoblasts (H9c2, ATCC CRL‐1446). BEAS‐2B cells were cultured in Airway Epithelial Cell Basal Medium

(4) Differential KEAP1/NRF2 mediated signaling widens the therapeutic window of redox-targeting drugs in SCLC therapyNat CommunApril 12, 2026Jana Samarin, Hana Nůsková, Piotr Fabrowski, Mona Malz, Eberhard Amtmann, Minerva J. Taeubert, Daniel Pastor-Flores, Daniel Kazdal, Roman Kurilov, Nicole de Vries, et al.DMS79 CRL-2049, NCI-H146 HTB-173, NCI-H2171 CRL-5929, NCI-H1963 CRL-5982, NCI-H378 CRL-5808, Beas-2B CRL-3588; DSMZ: HCC33 487), SCLC-16HC59 and the NSCLC cell line (ATCC: NCI-H1944 CRL-5907) were cultivated in

(5) Fc-free single-chain antibody mRNA therapy for airway infection of multidrug-resistant Pseudomonas aeruginosaNat CommunApril 9, 2026Mao Kinoshita, Ken Kawaguchi, Yuki Mochida, Nguyen B. T. Le, Atsushi Kainuma, Naoko Takeda-Miyata, Motohiro Kojima, Teiji Sawa, Satoshi Uchidaisolates was evaluated using human bronchial epithelial cells (SV40-immortalized BEAS-2B cells; ATCC CRL-3588, Manassas, VA, USA). Upon reaching 95% confluence, the cells were co-cultured with bacteria (5 × 107CFU/mL)

(6) In vitro and in vivo assessment of sporopollenin exine capsule preparations (SpECs) from Lycopodium clavatum sporesRSC AdvApril 1, 2026Ammar Hasan, Jeremiah Stanley, Abu Saleh Md Moin, Hamna Begam, Sana Waris, Marah Abdulhadi, Khaled Greish, Andrew N. Boa, Manyam Praveen Kumar, G. Roshan Deen, et al.operating at a voltage of 15 kV. In vitro studies Cell culture Human epithelial BEAS-2B cells (ATCC CRL-3588, Virginia, USA), a cell line used typically in toxicological studies, were revived as per ATCC recommendation.

(7) Vape-Associated lncRNA Transcript 1 (VALT1) Amplifies the Tumorigenic Effects of e-Cigarette Vapor in Lung Epithelial CellsNoncoding RNAMarch 16, 2026Daniel Angelo R. Mirador, Jose Lorenzo M. Ferrer, Kim Denyse Hao Lin, Reynaldo L. GarciaMaintenance of BEAS-2B Cells Immortalized BEAS-2B normal human bronchial epithelial cells (ATCC; Cat. No. CRL-3588) were maintained and cultured in T-75 culture flasks pre-coated with a 3 mL fibronectin-collagen coating

(8) PoMA-10: a dual-action antiviral disrupting SARS-CoV-2 Spike-ACE2 interaction and protecting lung tissueFront PharmacolMarch 12, 2026Soheun Lee, Suh Jin Yoon, Jihae Lim, Ji Hyun Oh, Jae-Sang Ryu, Gahee Kim, Hyunwoo Kang, Nayoon Jo, Sehan Lee, Sunbok Jang, et al.Drug Development Research Core Center. 2.3 Cell-based Spike-hACE2 binding inhibition assay BEAS-2B (ATCC, CRL-3588) and HEK293T (ATCC, CRL-3216) cells were maintained in DMEM with 10% FBS and transfected with pCMV3-human

(9) Activation of STAT3 in the COPD airway epitheliumERJ Open ResearchMarch 9, 2026Thomas Southworth, Charles Pilette, Alex Mulvanny, Andrew Higham, Pratama Anggi Saputra, Asmae Belhaj, Marylène Lecocq, Bruno Detry, Thomas Planté-Bordeneuve, Dave Singh, et al.was observed at 5 ng·mL−1. Western blots Western blots for Tyr705-phospho-(p-)STAT3 (product code: CRL-3588, ATCC, US) were performed on BEAS-2B cell line cultures stimulated with sputum supernatants (n=25),

(10) Multi-omics profiling reveals microenvironmental remodeling as a key driver of house dust mite-induced lung cancer progressionNeoplasiaMarch 1, 2026Shams Al-Azzam, Isabella Stuewe, Sunandini Sharma, Miki Yamada-Hara, Arisachi Tanaka, Kegan Stringer, Merna Behnam, Norah Al-Azzam, Shuvro Nandi, Maria Zhivagui, et al.lines,Experimental models: Cell lines,Experimental models: Cell lines Human: BEAS-2B cells,ATCC,"Cat# CRL-3588, RRID:CVCL_0168" Mouse: LL/2 (LLC1) cells,Dr. Jack Bui(UC San Diego),Cat# CRL-1642RRID:CVCL_4358 Mouse:

(11) Myoferlin is a component of late-stage vRNP trafficking vesicles for enveloped RNA virusesNature CommunicationsFebruary 7, 2026Stefano Bonazza, Hannah L. Turkington, Swathi Sukumar, Emily Peate, Hannah L. Coutts, Joshua J. Montgomery, Courtney Hawthorn, Erin M. P. E. Getty, Olivier Touzelet, Judit Barabas, et al.flaviviruses5. Methods Cells For this work immortalised A549 (ATCC; CCL-185), HEK 293 T (ATCC; CRL-3216), BEAS-2B (ATCC; CRL-3588), Hep-253 and MDCK (CCL-34) cells were used. All cells were cultured in DMEM supplemented with 1% Pen-Strep

(12) Preliminary study of cyto-impedance: Molecular profiling of functional impedance in motility-promoting treatment of normal cellsBiochem Biophys RepFebruary 4, 2026Chang-Zhi Li, Hong-Juan Zhou, Jin-Dong Chen, Jie Huang, Yi-Xiu Liu, Chao-Nan Qianfibroblast cell line HFF-1 (Cat. No. SCRC-1041, ATCC) and bronchial epithelial cell line Beas-2B (Cat. No. CRL-3588, ATCC) were cultured in Dulbecco's Modified Eagle Medium supplemented with 10 % fetal bovine serum in

(13) Integrated chemical and biological characterization of Hypericum perforatum extract using LC-MS/MS and in vitro functional assaysScientific ReportsJanuary 27, 2026Mehmet Ali Güzel, Turgay Kolaç, İrem Nur Menevşe, Muhammed Dündar, Rukiye Zengin, Abdussamat Güzel, Yılmaz UğurMCF‑7 (ATCC HTB‑22), A549 (ATCC CCL‑185), SH‑SY5Y (ATCC CRL‑2266), HeLa (ATCC CCL‑2), BEAS‑2B (ATCC CRL‑3588), and HCT‑116 (ATCC CCL‑247). All cell lines were cultured in DMEM supplemented with 10% fetal bovine

(14) Hybridization Approach Applied to Umbelliferon and Vanilloids toward New Inhibitors of Carbonic Anhydrases IX and XII with In Vitro Antiproliferative and Anti-inflammatory ActivitiesJournal of Medicinal ChemistryJanuary 22, 2026Francesco Melfi, Noemi Mencarelli, Simone Carradori, Marialucia Gallorini, Andrea Angeli, Giulio Poli, Amelia Cataldi, Ilaria D’Agostino, Andrea Di Credico, Angela Di Baldassarre, et al.the AMBER suite. 4.4 Cell-Based Assays 4.4.1 Cell Cultures Human bronchial epithelial (BEAS-2B; CRL-3588) and human lung carcinoma (A549; CCL-185) cell lines were purchased from ATCC. BEAS-2B and A549 cells

(15) Impact of Arsenite on Transient and Persistent Histone H3 Modifications and Transcriptional ResponseChemical Research in ToxicologyJanuary 19, 2026Tatjana Lumpp, Hassan Hijazi, Sandra Stößer, Eda Tekin, Lara Brunner, Franziska Fischer, Sabine Brugière, Delphine Pflieger, Andrea Hartwighumidified atmosphere. Passages 14–30 were utilized to ensure experimental consistency. BEAS-2B cells (ATCC CRL-3588), a human noncancerous bronchial epithelial cell line, were cultured in KGM medium on flasks coated

(16) Antibacterial, Redox, Cytotoxic, and Ecotoxic Properties of New Sol–Gel Silica-Copper-Based MaterialsPharmaceuticals (Basel)December 23, 2025Iliana Ivanova, Lilia Yordanova, Lora Simeonova, Miroslav Metodiev, Elena Nenova, Deyan Monov, Yoanna Kostova, Albena Bachvarova-Nedelcheva, Iva Kirova, Elitsa Pavlovaultrasonicated for 15 min before the serial dilutions within the range 1–1000 μg/mL. Cell lines BEAS-2B (ATCC-CRL-3588™) normal human bronchial epithelial cells, derived from autopsies of noncancerous individuals and human

(17) CPA3 drives the development of asthma by promoting the activation of the JAK/STAT6 pathwayRespiratory ResearchDecember 23, 2025Ke Wang, Ruhao Wu, Mingwei Fan, Ruohan Jia, Yize Liu, Yue Li, Pengfei Li, Yu Wang, Tianci Jiang, Zhe Chengalgorithm. Cell culture and treatment Normal human bronchial epithelial BEAS-2B cells (ATCC catalog number: CRL-3588) were cultured in RPMI-1640 medium (Solarbio, China), supplemented with 10% fetal bovine serum (Sigma-Aldrich,

(18) Synthesis, characterization, and anticancer potential of novel NHC ligands and their selenium complexes: a combined in vitro and in silico investigationRSC AdvDecember 22, 2025Boutheina Boualia, Abd el-Krim Sandeli, Enes Evren, İsmail Özdemir, Hüseyin Karci, Muhammed Dündar, İlknur Özdemir, Nevin Gürbüz, Ahmet Koç, Houssem Boulebd(ATCC CCL-247, human colon carcinoma), SH-SY5Y (ATCC CRL-2266, human neuroblastoma), and BEAS-2B (ATCC CRL-3588, human bronchial epithelial, non-cancerous). All cell lines were commercially obtained from American

(19) QSAR Modeling for Predicting IC50 and GI50 Values for Human Cell Lines Used in Toxicological StudiesInt J Mol SciDecember 15, 2025Alexey A. Lagunin, Elena Y. Lisitsa, Anastasia V. Rudik, Sergey M. Ivanov, Alexander V. Dmitriev, Elena S. Muraviova, Dmitry A. Filimonov, Vladimir V. PoroikovAccession Number,Description,Tissue,Interval of pIC50,Mean pIC50,Interval of pGI50,Mean pGI50 BEAS-2B,CRL-3588,Bronchial epithelial cells,Lung,2.6–8.1,4.9,, BJ,CRL-2522,Foreskin fibroblast,Skin,1.3–9.7,5.1,, CCD-18Co,CRL-1459,Fibroblasts,Colon,3.9–7.4,5.5,, GES1,-,Gastric

(20) The Incoming Influenza Genome Assembles a Host RBP Network that Orchestrates Viral RNA SynthesisbioRxivDecember 11, 2025Stephen Clarke, Deep B. Patel, Andrea Ascura, Caroline L. Wiser, Jennifer L. Pennise, Samantha M. Lisy, Manuel Ascano,Experimental models: Cell lines,Experimental models: Cell lines MDCK,ATCC,CCL-34 A549,ATCC,CCL-185 BEAS-2B,ATCC,CRL-3588 Oligonucleotides,Oligonucleotides,Oligonucleotides "Oligomers used in this study, see Table S6",This

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BEAS-2B from ATCC

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