Description
Hepatocytes were derived from iPS cells that were made from blood samples; specifically, samples taken from substance abusing (opioid addicted) patients.
Characterization of the cellsHepatocytes were analyzed morphologically as well as for Albumin Production. Cells test positive for Albumin production.Cells were also tested for active P450 metabolic enzymes. Using LC-MS activity was confirmed for CYP 1A, 1A2, 2B6, 2C19,2C9, 2D6, and 3A