Description
Our SARS-1 Pseudoviral Particles are replication-deficient MLV pseudotyped with the SARS-1 spike protein (Genbank Accession # AY278487). They also contain the ORF for firefly luciferase as a reporter. They establish a pseudovirus entry assay for SARS-1 as the spike protein mediated cell entry can be conveniently measured via the luciferase reporter activity. This pseudovirus assay isolates the SARS-1 viral entry from other steps of the viral infection cycle