THP-1 AP1-LUC2 from ATCC | Biocompare.com

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THP-1 AP1-LUC2

Product Specs
ItemTHP-1 AP1-LUC2
CompanyATCC
Price $1,285.00Supplier Page View Company Product Page
Catalog NumberTIB-202-AP1-LUC2
Volume1.0 mL
TissuePeripheral blood
SpeciesHuman (Hu)
DiseaseAcute Monocytic Leukemia
Cell LineTHP-1 AP-1-Luc2
Age1 year
Gendermale
Research Area3D cell culture, High-throughput screening, Assay development, Immune system disorder research, Immunology, Immuno-oncology, Cell and gene therapy (CGT) development
Quantity6.0 to 8.0 x 10^6
ApplicationsEnabling sensitive and quantitative assessment of signal transduction makes this reporter cell line ideal for in vitro bioluminescence assays to study signaling pathways, development of new drugs, and safety evaluation of new chemicals and drugs
TypeCell Biology

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(1) Elevated cyclic AMP inhibits NF-kappaB-mediated transcription in human monocytic cells and endothelial cellsThe Journal of biological chemistryAugust 23, 1996Ollivier V, Parry GC, Cobb RR, de Prost D, Mackman N.

(2) Inhibition of macrophage scavenger receptor activity by tumor necrosis factor-alpha is transcriptionally and post-transcriptionally regulatedThe Journal of biological chemistryMarch 29, 1996Hsu HY, Nicholson AC, Hajjar DP.

(3) Optimized use of the firefly luciferase assay as a reporter gene in mammalian cell linesBioTechniquesNovember 1, 1989Brasier AR, Tate JE, Habener JF.

(4) Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)International journal of cancerAugust 1, 1980Tsuchiya S, Yamabe M, Yamaguchi Y, Kobayashi Y, Konno T, Tada K.

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