Description
MagicQuant™ Pseudotyped PIV-2 HN Molecular Control is designed for use with assay procedures that test for PIV-2 HN genomic DNA and target the PIV-2 HN protein. Truncated DNA sequences from these genes are packaged into a specially designed recombinant viral vector and diluted in PBS. The product is ready-to-use for extraction and detection via an amplified nucleic acid test.
MagicQuant™ Pseudotyped PIV-2 HN Molecular Control utilizes a RNA enveloped retrovirus that has been developed as a viral vector for many years. The genes coding cis-acting elements for the viral associated LTR, ∮ and RRE, inserted with "target" sequences of interest are built. MagicQuant™ Pseudotyped PIV-2 HN Molecular Control, is the nucleic acid sequence of the PIV-2 HN gene wrapped in the outer membrane of the retrovirus. The resulting recombinant viral particles are efficiently packaged in HEK293 cells, but lack the genes required to produce new viral particles, and are therefore replication defective