Description
The olfactory bulb is located within the vertebrate forebrain, in which it functions to receive nerve endings/input from the nasal cavity. The sense of smell is associated with the nerve tissues of the olfactory bulb.Immortalized Mouse Olfactory Bulb Cells (OBC13) is immortalized with non-replicating retrovirus carrying the avian Myc gene. It is a sister derivative from the Immortalized Mouse Olfactory Bulb Cells (OBC1). The cells exhibit GalC (a marker for oligodendroglial lineage) marker, but has the absence of NF (neurofilament marker). Voltage-dependent potassium channels are expressed as well. OBC13 cells have been shown to form tumors in animal models, hence has the ability to be tumorigenic. It is a valuablein vitrotool for studies relating to the functions and the biology of the olfactory bulb