Description
Isolated from adult human lung tissue, their principle function is production of type III collagen, elastin, and proteoglycans of the extracellular matrix of the alveolar septa. Pulmonary fibroblasts play an important role in the repair and remodeling processes following injury. Fibroblast disorders like pulmonary fibrosis or hypoxia-induced pulmonary hypertension can also be investigated with cultured human primary pulmonary fibroblasts