IKCA1 (KCNN4) HEK293 Cell Line from BPS Bioscience, Inc. | Biocompare.com

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IKCA1 (KCNN4) HEK293 Cell Line

Ionomycin-induced increase of intracellular calcium level activates IKCA1 channel expressed in IKCA1 (KCNN4) HEK293 Cell Line Ionomycin-induced IKCA1 activation in the IKCA1 (KCNN4) HEK293 Cell Line is blocked by clotrimazole (CLT), an IKCA1 channel inhibitor

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BPS Bioscience, Inc. for
IKCA1 (KCNN4) HEK293 Cell Line

Description

Stable, recombinant HEK293 cell line expressing human IKCA1, also known as KCNN4 (Intermediate conductance calcium-activated potassium channel protein 4), IK1, hKCa4, and hSK4, GenBank Accession No. NM_002250

Product Specs
ItemIKCA1 (KCNN4) HEK293 Cell Line
CompanyBPS Bioscience, Inc.
Price $9,000.00Supplier Page View Company Product Page
Catalog Number90330
Quantity2 vials
ActivityN-terminal FLAG-tagged human IKCA1 has been stably expressed in HEK293 cell line and its expression was confirmed by Western blotting. Functional analysis of IKCA1 channel in the stable recombinant HEK293 was accomplished by using the membrane potential-sensitive fluorescence dye DiBAC4(3). When IKCA1-expressed HEK293 cells were stimulated with calcium-specific ionophore ionomycin to raise the intracellular level of Ca²⁺, IKCA1 channel was activated, leading to hyperpolarization and a decrease in cell fluorescence in the functional fluorescence assay with DiBAC4(3). This decrease of cell fluorescence was blocked by the IKCA1 channel inhibitor, clotrimazole (CLT)
TypeCell Line
Cell LineHEK293
ApplicationsDrug compound screening for activators or inhibitors of IKCA1, Functional assays for IKCA1, Efficient antigen for mouse immunization
Source/Expression SystemHEK293
human

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BPS Bioscience, Inc.

BPS Bioscience, Inc.

6405 Mira Mesa Blvd

Suite 100

San Diego, CA 92121

United States

Phone: 858-202-1401

Email: sales-team@bpsbioscience.com

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Website: https://bpsbioscience.com/

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