NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line from BPS Bioscience, Inc.

Supplier Images

NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line

hTNFα dose response in NF-κB reporter (Luc)-HCT-116 cells Inhibition of hTNFα-induced NF-κB activity by NF-κB inhibitor, IKK-16 dihydrochloride, in NF-κB reporter (Luc)-HCT-116 cells
NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line
NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line

Supplier Page from
BPS Bioscience, Inc. for
NF-κB Reporter (Luc) - HCT116 Recombinant Cell Line

Description

The NF-κB reporter (Luc)-HCT-116 cell line is designed to monitor nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or agonists of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene