TMEM16A-HEK293 Recombinant Cell Line from BPS Bioscience, Inc. | Biocompare.com

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TMEM16A-HEK293 Recombinant Cell Line

TMEM16A expressed in HEK293 produced I- influx after extracellular addition of I- with ionomycin. A) TMEM16A-HEK293 cells; B) WT-HEK293 cells Ionomycin-induced I- influx in TMEM16A-HEK293 cells was blocked by niflumic acid, a CaCC channel blocker

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BPS Bioscience, Inc. for
TMEM16A-HEK293 Recombinant Cell Line

Description

Stable, recombinant HEK293 cell line expressing human TMEM16A (transmembrane protein 16A, also called anoctamin 1, calcium-activated chloride channel (ANO1), accession number NM_018043)

Product Specs
ItemTMEM16A-HEK293 Recombinant Cell Line
CompanyBPS Bioscience, Inc.
Price $8,930.00Supplier Page View Company Product Page
Catalog Number90230
Quantity2 vials
ActivityN-terminal FLAG tagged human TMEM16A channel has been stably expressed in HEK293 cell line and its expression was confirmed by Western blotting. The CaCC activity of TMEM16A was characterized by an assay based on halide-sensitive yellow fluorescent protein (YFP) mutant whose fluorescence is quenched by increasing halide concentration. When TMEM16A-expressed HEK293 cells were stimulated with ionomycin to raise the intracellular level of Ca²⁺, TMEM16A produced I^- influx in HEK293 that triggered the rapid decrease of fluorescence of transfected YFP mutant. The ionomycin-induced I^- influx through TMEM16A was blocked by niflumic acid, a CaCC channel blocker
TypeCell Line
Cell LineHEK293
ApplicationsDrug compound screening for activators or inhibitors of TMEM16A, Functional assays for TMEM16A, Efficient antigen for mouse immunization
Source/Expression SystemHEK293
human

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BPS Bioscience, Inc.

BPS Bioscience, Inc.

6405 Mira Mesa Blvd

Suite 100

San Diego, CA 92121

United States

Phone: 858-202-1401

Email: sales-team@bpsbioscience.com

Company Profile

Website: https://bpsbioscience.com/

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