Description
Recombinant Jurkat cell line constitutively expressing a full length human TIGIT (T cell Immunoreceptor with Immunoglobulin and ITIM domain; VSTM3), and a firefly luciferase gene under the control of nuclear factor of activator T cells (NFAT) response element. Both TIGIT and NFAT constructs have been stably integrated into Jurkat cells. TIGIT expression has been confirmed by Western Blot, and TIGIT-specific NFAT response has been validated using a TIGIT ligand, CD155 (PVR)