NF- κB Reporter (Luc) - THP-1 Cell Line from BPS Bioscience, Inc.

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NF- κB Reporter (Luc) – THP-1 Cell Line

Dose response curve of NF-κB Reporter (Luc)-THP-1 Cell Line to hTNFα. Dose response curve of NF-κB Reporter (Luc)-THP-1 Cell Line to LPS. Dose response curve of NF-κB reporter (Luc)-THP-1 Cell Line to L18-MDP. Dose response curve of NF-κB reporter (Luc)-THP-1 Cell Line to hIL-1b. IKK-16 inhibition of the hTNFα induced stimulation in NF-κB reporter (Luc)-THP-1 Cell Line. IKK-16 inhibition of the LPS induced stimulation in NF-κB reporter (Luc)-THP-1 Cell Line. IKK-16 inhibition of the hIL-1b induced stimulation in NF-κB reporter (Luc)-THP-1 Cell Line.
NF- κB Reporter (Luc) - THP-1 Cell Line
NF- κB Reporter (Luc) - THP-1 Cell Line
NF- κB Reporter (Luc) - THP-1 Cell Line
NF- κB Reporter (Luc) - THP-1 Cell Line

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BPS Bioscience, Inc. for
NF- κB Reporter (Luc) - THP-1 Cell Line

Description

The NF-κB reporter (Luc)-THP-1 cell line is designed for monitoring nuclear factor Kappa B (NF-κB) signal transduction pathways. It contains a firefly luciferase gene driven by four copies of the NF-κB response element located upstream of the minimal TATA promoter. After activation by pro-inflammatory cytokines or stimulants of lymphokine receptors, endogenous NF-κB transcription factors bind to the DNA response elements, inducing transcription of the luciferase reporter gene