PathHunter® U2OS CALCR (No RAMP) β-Arrestin Cell Line from DiscoverX

Product Specs
ItemPathHunter® U2OS CALCR (No RAMP) β-Arrestin Cell Line
CompanyDiscoverX
Price $20,595.00Supplier Page View Company Product Page
Catalog Number93-0566C3
QuantityClone
ApplicationsGPCR β-Arrestin Assays
ReactivityHuman
TypeCell Line
TargetCALCR (No RAMP)
Research AreaGPCR β-Arrestin Assays

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DiscoverX

DiscoveRx Corporation 42501 Albrae St.

Fremont, California 94538

United States

Phone: (510) 979-1415

Email: CustomerServiceDRX@eurofins.com

Company Profile

Website: http://www.discoverx.com

(1) The dual amylin and calcitonin receptor agonist KBP-336 elicits a unique combination of weight loss, antinociception and bone protection – a novel disease-modifying osteoarthritis drugArthritis Research & TherapyJuly 12, 2024Khaled Elhady Mohamed, Anna Thorsø Larsen, Simone Melander, Frederik Andersen, Ellen Barendorff Kerrn, Morten Asser Karsdal, Kim Henriksenselectivity was evaluated using beta-arrestin assay on the U20S cell line for the calcitonin receptor (93-0566C3 DiscoverX) and CHO K1 CALCR RAMP3 for the amylin-3 receptor (93-0268C2, DiscoverX). For more details

(2) KBP-066A, a long-acting dual amylin and calcitonin receptor agonist, induces weight loss and improves glycemic control in obese and diabetic ratsMolecular MetabolismNovember 1, 2021K.V. Andreassen, A.T. Larsen, N. Sonne, K.E. Mohamed, M.A. Karsdal, K. Henriksenoverexpressing human receptors were used in in vitro potency screening: Calcitonin receptor (CTR; U20S CALCR, 93-0566C3 DiscoverX), Amylin 3 receptor (AMY3R; CHO K1 CALCR RAMP3, 93-0268C2, DiscoverX), CGRP receptor (CHO

(3) Optimization of tolerability and efficacy of the novel dual amylin and calcitonin receptor agonist KBP-089 through dose escalation and combination with a GLP-1 analogAmerican Journal of Physiology-Endocrinology and MetabolismNovember 1, 2017Sofie Gydesen, Kim Vietz Andreassen, Sara Toftegaard Hjuler, Lars I. Hellgren, Morten Asser Karsdal, Kim HenriksenRAMP3), and calcitonin gene-related peptide (CGRP) receptors (U2OS CALCR cells, DiscoverX catalog no. 93-0566C3; CHO-K1 CALCR-RAMP3, DiscoverX catalog no. 93-0268C2; and CHO-K1 CALCRL-RAMP1, DiscoverX catalog no.

(4) Prolonged Calcitonin Receptor Signaling by Salmon, but Not Human Calcitonin, Reveals Ligand BiasPLoS ONEMarch 18, 2014Kim Vietz Andreassen, Sara Toftegaard Hjuler, Sebastian G. Furness, Patrick M. Sexton, Arthur Christopoulos, Olivier Nosjean, Morten Asser Karsdal, Kim Henriksenand COS-7 1375 cell lines: U2OS CALCR cells (PathHunter U2OS CALCR β-arrestin cell line, DiscoverX: 93-0566C3) cultured in MEM Eagle 1× (30-2003, ATCC) supplemented with 10% Fetal Bovine Serum (FBS) (F2442, Sigma-Aldrich),

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PathHunter® U2OS CALCR (No RAMP) β-Arrestin Cell Line from DiscoverX

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PathHunter® U2OS CALCR (No RAMP) β-Arrestin Cell Line from DiscoverX

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