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PathHunter® U2OS Keap1-NRF2 Nuclear Translocation Cell Line
PathHunter® U2OS Keap1-NRF2 Nuclear Translocation Cell Line from DiscoverX
Be the first to write a review!
Citations:
(5)
Supplier Page
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DiscoverX for
PathHunter® U2OS Keap1-NRF2 Nuclear Translocation Cell Line
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Product Specs
Company Info
Citations
Reviews
Product Specs
Item
PathHunter® U2OS Keap1-NRF2 Nuclear Translocation Cell Line
Company
DiscoverX
Price
$20,595.00
Supplier Page
View Company Product Page
Catalog Number
93-0821C3
Quantity
Clone
Applications
Pathway Nuclear Translocation Assays
Reactivity
Human
Type
Cell Line
Target
Keap1-NRF2
Research Area
Pathway Nuclear Translocation Assays
Add to Compare List
DiscoverX
DiscoveRx Corporation 42501 Albrae St.
Fremont
,
California
94538
United States
Phone
: (510) 979-1415
Email: CustomerServiceDRX@eurofins.com
Company Profile
Website:
http://www.discoverx.com
Citations (5)
(1)
Design, Synthesis, and Biological Evaluation of Novel Vinyl Selenone Derivatives as Potent Nrf2 Activators for Atopic Dermatitis
Journal of Medicinal Chemistry
April 9, 2026
Jushin Kim, Yoowon Kim, Byungeun Kim, Elijah Hwejin Lee, Rium Kim, Jiwoo Park, Jaehwan Kim, Yonghan Kim, Sang In Park, Minsik Kang,
et al.
investigate Keap1-
Nrf2
nuclear translocation, the
PathHunter U2OS Keap1-Nrf2 nuclear translocation cell line
(
93-0821C3
,
DiscoverX
, Fremont, CA, USA) was cultured in AssayComplete
cell culture medium
(
92-3103G
,
DiscoverX
)
(2)
Covalent Inhibitors of KEAP1 with Exquisite Selectivity
Journal of Medicinal Chemistry
December 12, 2024
Imre Fejes, Piroska Markacz, Janos Tatai, Monika Rudas, Petra Dunkel, Mario Gyuris, Miklos Nyerges, Nicolas Provost, Valérie Duvivier, Philippe Delerive,
et al.
and acceptor enzyme in the nucleus (
PathHunter U2OS Keap1-NRF2 Nuclear Translocation Cell Line
, ref.
93–0821C3
,
DiscoverX
). PathHunter U2OS cells were grown in minimum essential medium (MEM) (ref.
30–2003
,
ATCC
),
(3)
Discovery and Optimization of a Series of Vinyl Sulfoximine-Based Analogues as Potent Nrf2 Activators for the Treatment of Multiple Sclerosis
Journal of medicinal chemistry
October 10, 2024
Kim Y, Kim J, Kim B, Kim R, Kim HJ, Lee EH, Kim J, Park J, Jeong Y, Park SI,
et al
.
°C in a 5% CO2 humidified incubator. The
PathHunter U2OS Keap1-NRF2 nuclear translocation cell line
(
93-0821C3
,
DiscoverX
, Fremont, CA, USA) used for the Keap1-
Nrf2
nuclear translocation
assay
was cultured in
AssayComplete Cell culture kit-103
(4)
Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator
ACS Medicinal Chemistry Letters
July 11, 2019
Ji Won Choi, Su Jeong Shin, Hyeon Ji Kim, Jong-Hyun Park, Hyeon Jeong Kim, Elijah Hwejin Lee, Ae Nim Pae, Yong Sun Bahn, Ki Duk Park
0.039 ± ± ± ± ± ± ± ± ± ± ± ± ± 0.015 0.047 0.009 0.026 0.015 0.016 0.050 0.028 0.024 0.030 0.036 0.025 0.024 a The Nrf2
functional assay
was accomplished by a PathHunter U2OS Nrf2 nuclear translocation cell line (
93-0821C3
,
DiscoveRx
). U2OS cells were plated at 13,000 cells/well in triplicate with various compound concentrations
(5)
Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction
Bioorganic & medicinal chemistry letters
May 15, 2013
Hu L, Magesh S, Chen L, Wang L, Lewis TA, Chen Y, Khodier C, Inoyama D, Beamer LJ, Emge TJ,
et al
.
Invitrogen
.
CellSensor™ ARE-bla Hep G2
Cell-based Assay
Protocol. 2006. p. 8 25.
DiscoveRx
. Product Booklet:
93-0821C3
. 2011. PathHunter® Keap1-Nrf2
Functional Assay
for chemiluminescent detection of activated Nrf2; p.
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PathHunter® U2OS Keap1-NRF2 Nuclear Translocation Cell Line from DiscoverX
Supplier Page
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$20,595.00
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