Description
These CD4+ T cells are specific for a peptide derived from tetanus toxoid bound to HLA-DRB1*01. They also recognize whole tetanus toxoid but only when presented by dendritic cells, not B-LCL. The figure on the left shows the levels of IL-5 produced in response to peptide or whole antigen presented by B-LCL or dendritic cells. The T cells also produce IFNg, IL-10, and IL-13. To see a larger figure right-click on the image and open in a new tab.
Healthy female donor, CMV negative. 5' 10" tall, 210 lbs. Her genotype at Fc gamma RIII alpha 158 is F/V