LIVERPOOL 10-Donor Pooled Human Cryopreserved Hepatocytes from BioIVT

Product Specs
ItemLIVERPOOL 10-Donor Pooled Human Cryopreserved Hepatocytes
CompanyBioIVT
Price Supplier Page View Company Product Page
Catalog NumberX008001
SpeciesHuman
Quantity5 million per vial
Source/Expression System10-Donor Pooled
TissueLiver
Cell Type (standardized)Hepatocytes
Tissue (standardized)Liver
Cell TypeHepatocytes
GenderMixed Gender
Breed / StrainHuman
Research AreaADME-Tox, Drug Discovery, DMPK

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BioIVT

PO Box 770

Hicksville, New York 11802

United States

Phone: 516-483-1196

Email: customerservice@bioivt.com

Company Profile

Website: www.bioivt.com

(1) N -Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad-Spectrum Antialphaviral ActivityJournal of Medicinal ChemistryNovember 13, 2025Anirban Ghoshal, John D. Sears, Mohammad Anwar Hossain, Edwin G. Tse, Stefanie Howell, Jane E. Burdick, Noah L. Morales, Sabian A. Martinez, Isabella Law, Zachary J. Streblow, et al.CMH-100CD-SQ, lot no. CMH100CD-V01422 and CMH100CD-V01699, pooled male CD-1) and human (BioIVT, cat. no. X008001, lot no. QZW and YIT, 10 pooled donors each) were used to assess compound stability. Ten mM stock solutions

(2) N -Alkyl Sulfamates as a New Class of nsP2 Cysteine Protease Inhibitors with Broad Spectrum Antialphaviral ActivitybioRxivJuly 4, 2025Anirban Ghoshal, John D. Sears, Mohammad Anwar Hossain, Edwin G. Tse, Stefanie Howell, Jane E. Burdick, Noah L. Morales, Sabian A. Martinez, Isabella Law, Zachary J. Streblow, et al.CMH100CD-SQ, lot no. CMH100CD-V01422 and CMH100CD-V01699, pooled male CD-1) and human (BioIVT, cat. no. X008001, lot no. QZW and YIT, 10 pooled donors each) were used to assess compound stability. 10 mM stock solutions

(3) Species-Dependent Metabolism of a Covalent nsP2 Protease Inhibitor with In Vivo Antialphaviral ActivityJ Med ChemMay 22, 2025Mohammad Anwar Hossain, Abigail K. Mayo, Anirban Ghoshal, Sharon Taft-Benz, Elizabeth Anderson, Noah L. Morales, Katia D. Pressey, Ava Vargason, Kim L. R. Brouwer, Nathaniel J. Moorman, et al.monkeys (RILD, cat. no. HP-SXH-02M, lot no. GRLG, pooled male cynomolgus), and humans (BioIVT, cat. no. X008001, lot no. QZW and YIT, 10 pooled donors each) were used. 10 mM stock solutions of 1 and positive control

(4) Species Dependent Metabolism of a Covalent nsP2 Protease Inhibitor with in Vivo Anti-alphaviral ActivitybioRxivJanuary 16, 2025Mohammad Anwar Hossain, Abigail K. Mayo, Anirban Ghoshal, Sharon A. Taft-Benz, Elizabeth J. Anderson, Noah L. Morales, Katia D. Pressey, Ava M. Vargason, Kim L. R. Brouwer, Nathaniel J. Moorman, et al.monkey (RILD, cat. no. HP-SXH-02M, lot no. GRLG, pooled male cynomolgus), and human (BioIVT, cat. no. X008001, lots no. QZW and YIT, 10 pooled donors each) were used. 10 mM stock solutions of 1 and positive control

(5) Discovery of a peripheral 5HT2A antagonist as a clinical candidate for metabolic dysfunction-associated steatohepatitisNature CommunicationsJanuary 20, 2024Haushabhau S. Pagire, Suvarna H. Pagire, Byung-kwan Jeong, Won-Il Choi, Chang Joo Oh, Chae Won Lim, Minhee Kim, Jihyeon Yoon, Seong Soon Kim, Myung Ae Bae, et al.hepatocytes used in the experiment is as follows: liverPool® 10-donor mixed gender human (BioIVT, Cat.No. X008001, lot EAV), male cynomolgus monkey (BioIVT, Cat.No. M00305, lot COJ), male Beagle dog (BioIVT, Cat.No.

(6) Fulvestrant-3-Boronic Acid (ZB716) Demonstrates Oral Bioavailability and Favorable Pharmacokinetic Profile in Preclinical ADME StudiesPharmaceuticals (Basel)July 26, 2021Jiawang Liu, Nirmal Rajasekaran, Ahamed Hossain, Changde Zhang, Shanchun Guo, Borui Kang, Hunsoon Jung, Hongjoong Kim, Guangdi Wangwith Pharmaron’s IACUC policies and procedures. 4.3. Metabolic Stability Hepatocytes of humans (#X008001), dogs (#M00205), rats (#M00005), and mice (#M005052) were purchased from BioIVT, NY, USA. Monkey hepatocytes

(7) Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction StudiesThe AAPS JournalSeptember 1, 2019Andrea Treyer, Mohammed Ullah, Neil Parrott, Birgit Molitor, Stephen Fowler, Per Arturssonvivo data. Cell Culture A pooled HH batch (BioreclamationIVT, LiverPool 10-donor HH, product no. X008001, Lot RBR) was used in the CYP inhibition assay and for determination drug uptake in suspended HH. After

(8) Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley ratsBMC Pharmacology and ToxicologyDecember 1, 2017Arnold Donkor Forkuo, Charles Ansah, David Pearson, Werner Gertsch, Amanda Cirello, Adam Amaral, Jaimie Spear, Colin W. Wright, Caroline Rynnsuspension hepatocytes were obtained from Bioreclamation IVT (catalogue numbers M00005 for rat and X008001 for human) and stored in the gas phase over liquid nitrogen until use. All experiments were carried

(9) Metabolic Profiling of Human Long-Term Liver Models and Hepatic Clearance Predictions from In Vitro Data Using Nonlinear Mixed-Effects ModelingThe AAPS JournalMarch 1, 2017Nicole A. Kratochwil et al.commercially available primary pooled cryopreserved hepatocytes from nontransplantable liver tissues were purchased (no. X008001, Lots ECO (ten donors) and URK (ﬁve donors); no. X008052, Lot JJR (ten donors)) from BioreclamationIVT

(10) Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug MetabolismDrug Metabolism and DispositionJanuary 7, 2016T Eric Ballard, Shuai Wang, Loretta M Cox, Mark A Moen, Stacy Krzyzewski, Okechukwu Ukairo, R Scott Obachsuspension hepatocyte studies a 10-donor mixed-gender pooled cryopreserved human hepatocyte Lot RTH (product no. X008001) was purchased from Celsis IVT (Baltimore, MD), and three-donor male beagle–pooled cryopreserved dog hepatocytes

(11) Synthesis and evaluation of derivatives of the proteasome deubiquitinase inhibitor b-AP15Chemical biology & drug designNovember 1, 2015Wang X, D'Arcy P, Caulfield TR, Paulus A, Chitta K, Mohanty C, Gullbo J, Chanan-Khan A, Linder S.metabolism Pooled cryopreserved human hepatocytes (10-donor mix) were obtained from Celsis IVT (product numbers X008001 and M005052; Chicago, IL, USA). Samples were analyzed by LC/MS using a Waters ACQUITY UPLC system plus

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LIVERPOOL 10-Donor Pooled Human Cryopreserved Hepatocytes from BioIVT

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LIVERPOOL 10-Donor Pooled Human Cryopreserved Hepatocytes from BioIVT

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