CloneSelect Imager (CSI and CSI FL) from Molecular Devices

Product Specs
ItemCloneSelect Imager (CSI and CSI FL)
CompanyMolecular Devices
Price Get Pricing Get Quote for this Product
Catalog NumberCloneSelect Imager (CSI and CSI FL)
Features (standardized)Self-Contained, Camera Compatible
TypeCell Imaging System
ApplicationsCell Line Development, Cell viability, Colony Forming Assay, Drug Sicovery and Development, Label-Free Cell Migration, Monoclonal Antibodies (mAbs), Monoclonality, Plasmid engineering in synthetic biology
Sample Type6- to 384-well plates
QuantityEA

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Molecular Devices

3860 N First Street

San Jose, California 95134

United States

Phone: 408-747-1700

Company Profile

Website: www.moleculardevices.com

(1) Targeting CRTC2 reverses STK11 mutant NSCLC tumor resistance to immunotherapyProc Natl Acad Sci U S AApril 28, 2026Dimitri Robay, Ole Ackermann, Laurent Laborde, Xingyi Shi, Federico Oreglia, Ramona Stump, Sabina Ciaghi, Giorgio G. Galli, Laura Holzer, Lorraine Villemin, et al.assessed by immunoblot after 5 d. Clones were subsequently derived by serial dilutions, selected by CloneSelect Imager (Molecular Devices), and confirmed by immunoblot. Transgenic cell lines were generated by lentiviral

(2) Ly6/uPAR Protein from Asterias rubens Starfish Stimulates Migration and Invasion of Human Epithelial and Immune CellsMarine DrugsDecember 19, 2025Ekaterina N. Lyukmanova, Tamara Y. Gornostaeva, Sergey V. Shabelnikov, Zakhar O. Shenkarev, Mikhail P. Kirpichnikov, Alexander S. Paramonov, Maxim L. Bychkovcells’ overgrowth, detachment and death. Pictures were analyzed after 0 and 24 h at 20× magnification at CloneSelect Imager (Molecular Devices, San Jose, CA, USA). The center of the plate was marked as a central reference point

(3) Novel Cerium- and Terbium-Doped Gadolinium Fluoride Nanoparticles as Radiosensitizers with Pronounced Radiocatalytic ActivityBiomedicinesJune 24, 2025Nikita A. Pivovarov, Danil D. Kolmanovich, Nikita N. Chukavin, Irina V. Savintseva, Nelli R. Popova, Alexander E. Shemyakov, Arina D. Filippova, Maria A. Teplonogova, Alexandra V. Yurkovskaya, Ivan. V. Zhukov, et al.at 37 °C in an atmosphere containing 5% CO2. The formation of colonies was monitored daily using a CloneSelect Imager plate reader (Molecular Devices, San Jose, CA, USA). After the colonies had formed in the control group

(4) Combination with a Low Dose of Doxorubicin Further Boosts the Antitumor Effect of SLURP-1 In Vivo and Associates with EGFR Down-RegulationActa NaturaeJanuary 1, 2025O. V. Shlepova, M. L. Bychkov, V. O. Shipunova, E. I. Shramova, M. A. Shulepko, T. Y. Gornostaeva, E. A. Kiseleva, I. D. Kukushkin, V. A. Kazakov, E. A. Tukhovskaya, et al.migration was measured by a scratch assay as described earlier [21, 43]. Images were obtained using CloneSelect Imager (Molecular Devices, United States), and the scratch area occupied by migrating cells was quantified

(5) Extracellular Vesicles from Plasma of Patients with Glioblastoma Promote Invasion of Glioblastoma Cells Even After Tumor ResectionBiomedicinesDecember 13, 2024Ekaterina N. Lyukmanova, Artem V. Kirichenko, Igor A. Medyanik, Konstantin S. Yashin, Mikhail P. Kirpichnikov, Maxim L. Bychkovthe experiment). Then, the cells migrating through the pores were photographed (100× magnification, CloneSelect Imager, Molecular Devices, San Jose, CA, USA). The number of invaded cells was quantified using the find maxima

(6) Sequence and Configuration of a Novel Bispecific Antibody Format Impacts Its Production Using Chinese Hamster Ovary (CHO) CellsBiotechnology and BioengineeringNovember 25, 2024Hirra Hussain, Angelica M. S. Ozanne, Tulshi Patel, Davide Vito, Mark Ellis, Matthew Hinchliffe, David P. Humphreys, Paul E. Stephens, Bernie Sweeney, James White, et al.at 4000 cells per well. After 14 days, single colonies (termed mini‐pools) were identified using a CloneSelect Imager (Molecular Devices) and transferred to 24‐well plates. The mini‐pools were grown in selective CD‐CHO

(7) Peptide Mimicking Loop II of the Human Epithelial Protein SLURP-2 Enhances the Viability and Migration of Skin KeratinocytesActa NaturaeJune 16, 2024O. V. Shlepova, T. Ya. Gornostaeva, I. D. Kukushkin, V. N. Azev, M. L. Bychkov, Z. O. Shenkarev, M. P. Kirpichnikov, E. N. Lyukmanovathe wells with scratched cell monolayers were analyzed after 0 and 24 h at 20× magnification using a CloneSelect Imager cell analysis system (Molecular Devices, USA). The images were digitized, and the scratch area was estimated

(8) Calcein-Modified CeO2 for Intracellular ROS Detection: Mechanisms of Action and Cytotoxicity Analysis In VitroCellsOctober 7, 2023Nikita N. Chukavin, Vladimir K. Ivanov, Anton L. Popovleft for cultivation for 48 h. During cultivation, the gap area between cells was photographed using a CloneSelect Imager system (Molecular Devices, San Jose, CA, USA), and images were taken every 12 h. At the end of cultivation,

(9) Boron Nanoparticle-Enhanced Proton Therapy for Cancer TreatmentNanomaterials (Basel)July 26, 2023Irina N. Zavestovskaya, Anton L. Popov, Danil D. Kolmanovich, Gleb V. Tikhonowski, Andrei I. Pastukhov, Maxim S. Savinov, Pavel V. Shakhov, Julia S. Babkova, Anton A. Popov, Ivan V. Zelepukin, et al.cultured at 37 °C in an atmosphere containing 5% CO2. Colony formation was monitored daily using a CloneSelect Imager plate reader (Molecular Devices, San Jose, CA, USA). After the completion of colony formation in the

(10) Engineering protein glycosylation in CHO cells to be highly similar to murine host cellsFrontiers in Bioengineering and BiotechnologyFebruary 16, 2023Shivani Gupta, Bhavana Shah, Coral Shek Fung, Pik Kay Chan, Devin L. Wakefield, Scott Kuhns, Chetan T. Goudar, James M. Piretplates with one cell per well to identify single-cell clones. Plates were imaged on a high-throughput CloneSelect™ Imager (Molecular Devices, Sunnyvale, CA) to verify clonality on Day 0 and monitor clone expansion on Days

(11) Trisomy 21 increases microtubules and disrupts centriolar satellite localizationMolecular Biology of the CellJuly 1, 2022Bailey L. McCurdy, Cayla E. Jewett, Alexander J. Stemm-Wolf, Huy Nguyen Duc, Molishree Joshi, Joaquin M. Espinosa, Rytis Prekeris, Chad G. Pearsonedited pooled populations by manually seeding approximately one cell into each well of 96-well plates. CloneSelect Imager (Molecular Devices; CSI8086) was used to visually select wells with a single colony. These single colonies

(12) Extracellular Vesicles Derived from Acidified Metastatic Melanoma Cells Stimulate Growth, Migration, and Stemness of Normal KeratinocytesBiomedicinesMarch 12, 2022Bychkov ML, Kirichenko AV, Mikhaylova IN, Paramonov AS, Yastremsky EV, Kirpichnikov MP, Shulepko MA, Lyukmanova EN.additional 48 h. After that, plates were imaged at 50× and 30× magnification using the E-scope mode of the CloneSelect Imager (Molecular Devices, San Jose, CA, USA). The 6 photos of each well were taken, and the keratinocytes

(13) Mambalgin-2 Inhibits Growth, Migration, and Invasion of Metastatic Melanoma Cells by Targeting the Channels Containing an ASIC1a Subunit Whose Up-Regulation Correlates with Poor Survival PrognosisBiomedicinesSeptember 26, 2021Bychkov ML, Kirichenko AV, Shulepko MA, Mikhaylova IN, Kirpichnikov MP, Lyukmanova EN.normal or acidic medium, respectively, every 48 h. After that, the photo of the cells were taken using CloneSelect Imager (80× magnification, Molecular Devices, San Jose, CA, USA), and the cell viability and cell cycle were

(14) GliPR1 knockdown by RNA interference exerts anti-glioma effects in vitro and in vivoJournal of neuro-oncologyMay 1, 2021Scheuring UJ, Ritter S, Martin D, Schackert G, Temme A, Tietze S.either left untreated or treated with 1 µg/ml doxycycline; confluency was assessed over 7 days using the CloneSelect Imager (Molecular Devices, LLC, San José, CA, USA). Investigations of stable GliPR1 knockdown used the three

(15) Therapy for Argentine hemorrhagic fever in nonhuman primates with a humanized monoclonal antibodyProceedings of the National Academy of Sciences of the United States of AmericaMarch 16, 2021Zeitlin L, Cross RW, Geisbert JB, Borisevich V, Agans KN, Prasad AN, Enterlein S, Aman MJ, Bornholdt ZA, Brennan MB, et al.from the top isolate by limiting the dilution and subsequent verification of monoclonality using a CloneSelect imager (Molecular Devices). Production of hu199 mAb for in vivo studies was carried out using a clonal cell

(16) SLURP-1 Controls Growth and Migration of Lung Adenocarcinoma Cells, Forming a Complex With α7-nAChR and PDGFR/EGFR HeterodimerFrontiers in cell and developmental biologyJanuary 1, 2021Bychkov ML, Shulepko MA, Shlepova OV, Kulbatskii DS, Chulina IA, Paramonov AS, Baidakova LK, Azev VN, Koshelev SG, Kirpichnikov MP, et al.with rSLURP-1 or peptide for 48 h. Pictures were analyzed after 0 and 24 h at 20× magnification at CloneSelect Imager (Molecular Devices, United States). The center of the plate was marked as a central reference point

(17) Multiplexed clonality verification of cell lines for protein biologic productionBiotechnology ProgressJuly 1, 2020Sofie A. O'Brien, Juhi Ojha, Paul Wu, Wei‐Shou Huwere selected using Puromycin in 96 wells, and surviving clones were isolated after monitoring by a CloneSelect Imager (Molecular Devices, San Jose, CA). Subsequent subcloning was performed via limiting dilution. Probe

(18) Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cellsOncotargetApril 7, 2020Lamb DJ, Rust A, Rudisch A, Glüxam T, Harrer N, Machat H, Christ I, Colbatzky F, Wernitznig A, Osswald A, et al.assays 24-well plates were seeded at 10 000 cells per well in 500 μL medium. They were imaged daily on the CSI (CloneSelect Imager, Molecular Devices) which measured the confluence (representing cell number) of the wells, to generate

(19) Mycoplasma hyorhinis infection promotes gastric cancer cell motility via β-catenin signalingCancer medicineSeptember 1, 2019Liu X, Rong Z, Shou C.were added. After 24, 48, and 72 hours, cell proliferation was quantified by cell confluence with a CloneSelect Imager (Molecular Devices, Sunnyvale, CA). 2.10 Quantitative RT‐PCR (qRT‐PCR) Total RNA was isolated from

(20) Topoisomerase inhibitors promote cancer cell motility via ROS-mediated activation of JAK2-STAT1-CXCL1 pathwayJournal of experimental & clinical cancer research : CRAugust 22, 2019Liu J, Qu L, Meng L, Shou C.in triplicate wells of 24-well plate (1.5 × 104 cells/well). The confluences were quantified by the CloneSelect Imager (Molecular Devices, Sunnyvale, CA, USA) every 24 h. Cell migration and invasion assays Cell migration assay

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