8- Bromoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer (Rp-8-Br-cGMPS) from MyBioSource.com

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8- Bromoguanosine- 3', 5'- cyclic monophosphorothioate, Rp- isomer (Rp-8-Br-cGMPS)

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Description

C10H10BrN5O6PS.Na; MW 462.2; lambdamax 260 nm; epsilon 16200; sodium salt, purity > 99% HPLC. For other salt forms please inquire. Inhibitor of protein kinase G I alpha and I beta. Resistant against mammalian cyclic nucleotide- dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane-permeant compared to cyclic GMP or Rp-cGMPS. Detailed technical information and updated reference list available on request. Reference: Zhuo et al., Nature 368, 635 - 639 (1994)