Recombinant Mouse Ctla4, His tagged Ctla4-3307M from Creative BioMart

Product Specs
ItemRecombinant Mouse Ctla4, His tagged
CompanyCreative BioMart
Price Supplier Page View Company Product Page
Catalog NumberCtla4-3307M
SpeciesMouse
Source/Expression SystemHEK293
Gene NameCtla4, His tagged (Mouse)
Conjugate/TagHis
Purity>90 % as determined by SDS-PAGE
NCBI Full Gene Namecytotoxic T-lymphocyte-associated protein 4
NCBI Gene AliasesCd152, Ctla-4, Ly-56
ApplicationsFor research and further manufacturing use
Molecule NameCtla4
Molecular WeightThe protein has a calculated MW of 15.9 kDa. The protein migrates as 25-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation
Size1
Activity1. Immobilized recombinant mouse CTLA4-His at 2 µg/ml (100 µl/well) can mouse CD80-Fc. The EC50 of mouse CD80-Fc is 1-9 ng/ml. 2. Immobilized recombinant mouse CTLA4-His at 10 µg/ml (100 µl/well) can human B7-1-Fc. The EC50 of human B7-1-Fc is 2-14 ng/ml. 3. Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 for this effect is 0.1-0.5µg/mL when stimulated with 1 µg/mL Recombinant Human B7-1/CD80

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Recombinant Mouse Ctla4, His tagged from Creative BioMart