Description
This protein is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras
Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene