ChromPure Human IgG, Fc fragment 009-000-008 from Jackson ImmunoResearch Laboratories, Inc.

Product Specs
ItemChromPure Human IgG, Fc fragment
CompanyJackson ImmunoResearch Laboratories, Inc.
Price $224.00Supplier Page View Company Product Page
Catalog Number009-000-008
Size1 mg
Molecule NameIgG, Fc fragment specific
Conjugate/TagUnconjugated
PurityBased on immunoelectrophoresis at an antigen concentration of 20 mg/ml, the pattern of precipitation against goat anti- whole serum is the same as that against goat anti- IgG, Fc fragment specific. No precipitin line was detected against goat anti- IgG, F(ab')2 fragment specific; rabbit anti- IgG, F(ab')2 fragment specific; goat anti- IgM, Fc5m fragment specific; or goat anti- IgA, a chain specific
ReactivityHuman
FormatChromPure
Validated Species ReactivityHuman (Hu)
IsotypeFc

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Jackson ImmunoResearch Laboratories, Inc.

872 West Baltimore Pike

West Grove, Pennsylvania 19390

United States

Phone: 1-800-FOR-JAXN (367-5296)
Phone: 610-869-4024
Fax: 610-869-0171

Email: cuserv@jacksonimmuno.com

Company Profile

Website: www.jacksonimmuno.com

(1) Tumor cell-based liquid biopsy using high-throughput microfluidic enrichment of entire leukapheresis productNature communicationsJanuary 2, 2025Mishra A, Huang SB, Dubash T, Burr R, Edd JF, Wittner BS, Cunneely QE, Putaturo VR, Deshpande A, Antmen E, et al.-cell sorting The enriched leukopak by LPCTC-iChip were Fc blocked (Jackson ImmunoResearch Laboratories, Cat# 009-000-008) and then immunostained with AF488-conjugated EpCAM (Cell signaling, Cat# 5198) / PSMA (Invitrogen,

(2) Identification of a Notch transcriptomic signature for breast cancerBreast Cancer ResearchJanuary 3, 2024Eike-Benjamin Braune, Felix Geist, Xiaojia Tang, Krishna Kalari, Judy Boughey, Liewei Wang, Roberto A. Leon-Ferre, Antonino B. D’Assoro, James N. Ingle, Matthew P. Goetz, et al.minor modifications: 1µg rat Jagged1-Fc (cat #599-JG, R and D systems) or ChromPure Human IgG, Fc (cat #009-000-008, Jackson ImmunoResearch) was used instead of 2 µg. Activation of Notch signalling in the cell lines

(3) An ACE2 decamer viral trap as a durable intervention solution for current and future SARS-CoVEmerging Microbes & InfectionsDecember 11, 2023Hailong Guo, Bomsoo Cho, Paul R. Hinton, Sijia He, Yongjun Yu, Ashwin Kumar Ramesh, Jwala Priyadarsini Sivaccumar, Zhiqiang Ku, Kristen Campo, Sarah Holland, et al.Cat#: 18-1105). The biosensors were blocked with a control Fc protein (Jackson ImmunoResearch Cat#: 009-000-008) at 150 μg/mL for 200 s to occupy the free protein A. The sensors were dipped in threefold serially

(4) Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3ADevelopmental dynamics : an official publication of the American Association of AnatomistsJanuary 1, 2023Cantu-Guerra HL, Papazian MR, Gorsky AL, Alekos NS, Caccavano A, Karagulyan N, Neef J, Vicini S, Moser T, Coate TM.SEMA3A-Fc chimera protein (R&D Systems 1250-S3–025), control human IgG-Fc (Jackson ImmunoResearch, 009–000-008), 5 μM AMPA receptor inhibitor NBQX (Abcam AB120160), or 10 μM NMDA receptor inhibitor CPP (Abcam 120

(5) Indirect Immobilised Jagged-1 Enhances Matrisome Proteins Associated with Osteogenic Differentiation of Human Dental Pulp Stem Cells: A Proteomic StudyInternational journal of molecular sciencesNovember 11, 2022Chansaenroj A, Kornsuthisopon C, Roytrakul S, Phothichailert S, Rochanavibhata S, Fournier BPJ, Srithanyarat SS, Nowwarote N, Osathanon T.PBS. The final coating step was performed by incubating 10 nM of human IgG Fc fragment (hFc, cat. no. 009000008, Jackson Immuno Research Labs, West Grove, PA, USA) and 10 nM rhJagged1/Fc recombinant protein (cat.

(6) GPC3-Unc5 receptor complex structure and role in cell migrationCellOctober 13, 2022Akkermans O, Delloye-Bourgeois C, Peregrina C, Carrasquero-Ordaz M, Kokolaki M, Berbeira-Santana M, Chavent M, Reynaud F, Raj R, Agirre J, et al.(PEI),SIGMA-Aldrich,Cat#208727 Sucrose,SIGMA-Aldrich,Cat#S0389-500G "Human IgG, Fc fragment",Jackson Immunoresearch,Cat#009-000-008-JIR NDSB-256,Hampton Research,Cat#HR2-705 RPMI-1640 Medium,LGC Standards,Cat#ATCC 30-2001 1-Step

(7) A homogeneous bioluminescent immunoassay for parallel characterization of binding between a panel of antibodies and a family of Fcγ receptorsScientific reportsJuly 16, 2022Nath N, Godat B, Flemming R, Urh M.,Athens Research & Technology,16-16-090707-4 5,Human IgG,Rockland Immunochemical,009-0102 6,Human IgG Fc Fragment,Jackson ImmunoResearch,009-000-008 7,"Human IgG, Fab Fragment",Rockland Immunochemical,009-0104 8,"Human IgG, F(ab)2 Fragment",Rockland Immunochemical

(8) An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer's diseaseNat AgingJuly 1, 2022Jiang Y, Zhou X, Wong HY, Ouyang L, Ip FCF, Chau VMN, Lau SF, Wu W, Wong DYK, Seo H, et al.them with murine recombinant sST2-Fc protein (240 ng per pump; 10 μg ml−1) or human IgG (as a control; 009-000-008; Jackson ImmunoResearch) in artificial CSF (119 mM NaCl, 2.5 mM KCl, 2.5 mM CaCl2·2H2O, 1 mM NaH2PO4·2H2O,

(9) Targeting hypersialylation in multiple myeloma represents a novel approach to enhance NK cell–mediated tumor responsesBlood AdvancesJune 14, 2022John Daly, Subhashis Sarkar, Alessandro Natoni, Jessica C. Stark, Nicholas M. Riley, Carolyn R. Bertozzi, Mattias Carlsten, Michael E. O'Dwyer(1138-SL-050 and 1139-SL-050), anti-human immunoglobulin G Fc fragment was from Jackson ImmunoResearch (009-000-008). Maackia amurensis agglutinin was from Vector Laboratories (B-1265), 3Fax-Peracetyl Neu5Ac was from

(10) Non-canonical Wnt signaling participates in Jagged1-induced osteo/odontogenic differentiation in human dental pulp stem cellsScientific reportsMay 9, 2022Kornsuthisopon C, Chansaenroj A, Manokawinchoke J, Tompkins KA, Pirarat N, Osathanon T.culture plates between each step. For the control condition, the human IgG Fc fragment (hFc, cat. no. 009000008, Jackson Immuno Research Labs, USA) was placed in the wells in amounts equal to the Jagged1 ligand. To

(11) Notch-mediated Ephrin signaling disrupts islet architecture and β cell functionJCI insightMarch 22, 2022Bartolomé A, Suda N, Yu J, Zhu C, Son J, Ding H, Califano A, Accili D, Pajvani UB.(374-EA), and recombinant mouse TGF-β1 (7666-MB) from R&D Systems, Bio-Techne. Human IgG Fc fragment (009-000-008) and anti–Fc–Alexa Fluor 488 (709-545-098) were from Jackson ImmunoResearch. Glucose tolerance tests

(12) Discovery and engineering of an anti-TREM2 antibody to promote amyloid plaque clearance by microglia in 5XFAD micemAbsJanuary 1, 2022Zhao P, Xu Y, Fan X, Li L, Li X, Arase H, Tong Q, Zhang N, An Z.During the entire blocking and incubation, 0.1 mg/mL human IgG1 Fc fragment (Jackson Immunoresearch, 009–000-008) was added together with 1% BSA PBS to block interactions with Fc receptors. Microglia viability Human

(13) A Norrin/Wnt surrogate antibody stimulates endothelial cell barrier function and rescues retinopathyEMBO molecular medicineJuly 7, 2021Chidiac R, Abedin M, Macleod G, Yang A, Thibeault PE, Blazer LL, Adams JJ, Zhang L, Roehrich H, Jo HN, et al.BLI response of 0.4–0.6 nm. Remaining binding sites on the sensors were then saturated with human Fc (009‐000‐008, Jackson ImmunoResearch). Antigen or control (Fc alone) coated sensors were transferred to 100 nM of

(14) Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizerNature communicationsOctober 14, 2020Apóstolo N, Smukowski SN, Vanderlinden J, Condomitti G, Rybakin V, Ten Bos J, Trobiani L, Portegies S, Vennekens KM, Gounko NV, et al.analog",Thermo-Fisher,Cat#: F34653 "ChromPure Human IgG, Fc fragment",Jackson Immunoresearch,Cat#: 009-000-008;RRID: AB_2337046 AffiniPure Fab Fragment Donkey anti-Mouse IgG (H + L),Jackson Immunoresearch,Cat#:

(15) Hypoxia Triggers the Intravasation of Clustered Circulating Tumor CellsCell reportsSeptember 8, 2020Donato C, Kunz L, Castro-Giner F, Paasinen-Sohns A, Strittmatter K, Szczerba BM, Scherrer R, Di Maggio N, Heusermann W, Biehlmaier O, et al.Ephrin-B2-hFC chimera (R&D Biosystem, 496-EB-200) or ChromPure IgG hFC fragment (Jackson Immuno research, 009-000-008) for 3 hours and subsequently lysed. Anti-hEphB4 (R&D systems, AF3038-SP) and anti-mEphB4 (R&D systems,

(16) Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephalyeLifeSeptember 2, 2020Mingi Hong, Annabel Christ, Anna Christa, Thomas E Willnow, Robert S Kraussng/ml Peptide, recombinant protein FGF2 R and D Systems Peptide, recombinant protein IgG Fc (human) Jackson Laboratories 009-000-008 Peptide, recombinant protein Protein G-agarose beads Roche 11243233001 Peptide, recombinant protein Anti-AP-conjugated

(17) NOTCH2 participates in Jagged1-induced osteogenic differentiation in human periodontal ligament cellsScientific reportsAugust 7, 2020Manokawinchoke J, Sumrejkanchanakij P, Boonprakong L, Pavasant P, Egusa H, Osathanon T.cat. no. 1277-JG, R&D Systems, Minneapolis, MN, USA) for 2 h. Human IgG Fc fragments (hFc, cat. no. 009000008, Jackson Immuno Research Labs, USA) were used in the control conditions. Polymerase chain reaction (PCR

(18) Vangl2 acts at the interface between actin and N-cadherin to modulate mammalian neuronal outgrowtheLifeJanuary 7, 2020Steve Dos-Santos Carvalho, Maite M Moreau, Yeri Esther Hien, Mikael Garcia, Nathalie Aubailly, Deborah J Henderson, Vincent Studer, Nathalie Sans, Olivier Thoumine, Mireille MontcouquiolR and D Systems) while the other half was incubated with 4 µg of ChromPure Human IgG, Fc fragment (009-000-008 Jackson ImmunoResearch) alone (control experiment to test adhesion specificity). Beads were rinsed again

(19) Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinomaMolecular OncologyNovember 1, 2019Michael DiPrima et al.EphrinB2‐Fc (R&D Systems; 7397‐EB‐050) and human IgG‐Fc (JacksonImmuno Research, West Grove, PA, USA; 009‐000‐008) were individually clustered with anti‐human IgG‐Fc‐specific antibody (ThermoFisher; 628400) for 1 h

(20) Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during DevelopmentThe Journal of neuroscience : the official journal of the Society for NeuroscienceAugust 14, 2019Jung JS, Zhang KD, Wang Z, McMurray M, Tkaczuk A, Ogawa Y, Hertzano R, Coate TM.chimera protein (R&D Systems, 6680-S5-050) or control purified human IgG-Fc (Jackson ImmunoResearch, 009-000-008) were added to the medium at a final concentration of 23 nM. Typically, to induce cellular events such

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ChromPure Human IgG, Fc fragment from Jackson ImmunoResearch Laboratories, Inc.

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Jackson ImmunoResearch Laboratories, Inc.

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ChromPure Human IgG, Fc fragment from Jackson ImmunoResearch Laboratories, Inc.

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