Description
GPRASP2cDNA encodes a 548 amino acid protein that contains a 19 amino acid signalsequence and is comprised of many conserved domains: WAP, follistatin/Kazal,immunoglobulin, two tandem Kunitz, and netrin. Based on the order of theseconserved domains, GPRASP2 is also known as WFIKKN. Another related proteinwhich contains the same domain structure is called WFIKKNRP (WFIKKN-relatedprotein), or GASP-1. WAP, follistatin, Kunitz and netrin domains are allimplicated in protease inhibition, and the GASP proteins may be multivalent proteaseinhibitors