Human CD120b Protein (OPSA11061) from Aviva Systems Biology

Product Specs
ItemHuman CD120b Protein (OPSA11061)
CompanyAviva Systems Biology
Price $469.00Supplier Page View Company Product Page
Catalog NumberOPSA11061
Size20ug
Purity>98% by SDS PAGE and HPLC analysis, Purified recombinant CD120b expressed in E.coli
Molecular Weight18.9kD (174 amino acid residues)
SpeciesHuman
Molecule NameTumor necrosis factor receptor superfamily member 1B
NCBI Full Gene NameTNF receptor superfamily member 1B
NCBI Gene AliasesTNFR1B, p75, CD120b, p75TNFR, TNFBR, TBPII, TNF-R-II, TNFR2, TNFR80, TNF-R75
TypeProtein
FormatLyophilized. Phosphate buffered saline
ApplicationsELISA, FC, FLISA, IF, SDS-PAGE, WB
Concentration0.1 mg/ml

Specifications/Features

Specificity: The soluble form of human CD120b, otherwise known as sTNF receptor type II (sTNFRII), is a member of the tumour necrosis factor receptor (TNFR) superfamily, produced by proteolytic cleavage of the membrane form by the metalloprotease TACE. CD120b plays a key role in regulating the inflammatory response, acting as a receptor for both tumour necrosis factor alpha (TNF-alpha) and TNF-beta, and is also involved in programmed cell death and anti-viral activity. sTNFRII acts as an inhibitor of TNF-alpha induced responses, by acting as a decoy receptor.

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