Description
The Alt-R™ HDR Enhancer Protein is a recombinant, pathway-specific genome editing reagents designed to significantly improve the precision and efficiency of CRISPR-mediated homology-directed repair (HDR). Engineered to enhance HDR rates across diverse and difficult-to-edit cell types—including iPSCs and HSPCs—this protein enables more reliable knock-in editing without increasing off-target effects, chromosomal translocations, or cytotoxicity. Compatible with multiple CRISPR-Cas systems and manufactured under rigorous quality standards by Aldevron, the HDR Enhancer Protein integrates seamlessly into existing discovery and therapeutic development workflows. Available in RUO format with CGMP options coming soon, it accelerates translational timelines by boosting edited cell yields and supporting smooth progression from research to clinical applications.