WNK3, Active AAA74115 from AAA Biotech, LLC

Description

Recombinant human WNK3 (1-571) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. The gene accession number is NM_001002838.
WNK3 is a member of serine-threonine protein kinases, which was named the with-no-lysine family (1). WNK3 is expressed in several tissues including kidney and brain (1). WNK3 can regulate the activity of the electroneutral cation-coupled chloride cotransporters by activating NKCC1/2 and NCC and inhibiting KCCs (1). WNK3 kinase function is required for normal blood pressure homeostasis and the control of neuronal excitability (2). Also, overexpression of WNK3 increases the survival of Hela cells through caspase-3 pathway (3)

Product Specs
ItemWNK3, Active
CompanyAAA Biotech, LLC
Price $455.00Supplier Page View Company Product Page
Catalog NumberAAA74115
Quantity0.05 mg, 5x0.5 mg, 4x0.5 mg, 3x0.5 mg, 2x0.5 mg, 0.01 mg, 0.5 mg
TypeRecombinant Protein
FormatRecombinant protein stored in 50mM Tris-HCl, pH7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, and 25% glycerol
ApplicationsWB (Western Blot), Kinase Assay
Molecular Weight~91kDa
StorageStore product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles
HostSf9 insect cells
NCBI Full Gene NameWNK lysine deficient protein kinase 3
NCBI Gene AliasesPRKWNK3
ProteinWNK3