IL-2, PeproTech 200-02-50UG from Thermo Fisher Scientific

Product Specs
ItemIL-2, PeproTech
CompanyThermo Fisher Scientific
Price Supplier Page
Catalog Number200-02-50UG
Storage-20°C
Formatno preservative
ApplicationsCell Culture
Quantity50UG
ProteinIL-2
TypeRecombinant
SpeciesHuman
NCBI Full Gene Nameinterleukin 2
NCBI Gene AliasesIL-2, TCGF, lymphokine

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Thermo Fisher Scientific

81 Wyman Street

Waltham, MA 02451

United States

Phone: 800-678-5599
Fax: 800-331-2286

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Website: www.thermofisher.com

(1) Hematopoietic cell‑specific knockout Hspa9 impairs natural killer cell function and alters the Akt/mTOR axis in miceExperimental and Therapeutic MedicineJuly 24, 2026Xiaokang Zeng, Jieyu Zhang, Caiying Liang, Jie Yao, Zuqiang WuVav-cre mice were cultured in RPMI 1640 medium containing recombinant human IL-2 (1,000 IU/ml) (cat. no. 200-02-50UG; Thermo Fisher Scientific, Inc.) for 4 h. For the detection the mitochondrial mass, NK cells were stained

(2) MiR-139 modulates CD8+ T cells exhaustion by targeting CD28 in breast canceriScienceJuly 17, 2026Jianrong Chen, Haiyong Zhang, Yanting Lv, Xiufang Li, Mengjun HuD7304-1SET X-VIVO 15 serum-free medium,Lonza,Cat.No. 02-060Q Human IL-2 Recombinant Protein,PeproTech,Cat.No. 200-02-50UG Human Fractalkine/CX3CL1 ELISA Kit,Thermo Fisher Scientific,Cat.No. EHCX3CL1 Human SDF-1 beta/CXCL12B ELISA Kit

(3) MINFLUX nanoscopy to study the NK cell immune synapseMethods in Cell BiologyMay 23, 2026Nora Ross, Daniel P. Leaman, Jessica Matthias, Michael B. Zwick, Emily M. Mace, Scott C. Henderson, Charles Daniel Murin(CRL-2407, ATCC)Myleocult™ H5100 (05150, Stemcell Tech)Human IL-2 recombinant protein, PeproTech® (200-02-50ug, Thermo Fisher)Gibco™ Fetal Bovine Serum, heat inactivated (A5256801, Thermo Fisher)Gibco™ RPMI 1650

(4) Feeder-free generation of functional dendritic cells from human pluripotent stem cellsJ Immunother CancerMay 13, 2026Wei-Hung Jung, Andrew Khalil, Yoav Binenbaum, Joshua M Price, Kyle H Vining, Tenzin Lungjangwa, Miguel C Sobral, Rudolf Jaenisch, David J Mooneypenicillin-streptomycin, and 55 µM β-mercaptoethanol, with the addition of IL-2 (50 ng/mL−1; PeproTech, 200–02-50UG). To evaluate T-cell proliferation, T cells were stained with CFSE (Thermo Fisher, C34554) according

(5) The absence of B7-H4 inhibits PD-L1 expression by driving a methylation of PD-L1 promoter in breast cancer cellsBreast Cancer ResearchApril 22, 2026Linlin Zhou, Mei Ruan, Jichun Wu, Qiongwen Wu, Yonglei Xiao, Chen-Wei Yu, Qiuyu Zhangactivate T cells, anti-human CD28 (5 µg/mL, BioLegend, 302933) and recombinant IL-2 (100 IU/mL, Peprotech, 200-02-50UG) were added into the cell media for 5 days. The activated T cells were then labeled with 3 µM carboxyfluorescein

(6) DNAM-1 mediates NK-cell activation and host-pathogen interaction via direct binding to fungal cell wall proteasesCommun BiolApril 13, 2026Fariha Natasha, Linda Heilig, Dominic A. Helmerich, Christian Luther, Jan Springer, Bipasa Kar, Matthias Drobny, Lydia Kasper, Carla Schuh, Marcus Dittrich, et al.#130114429), 5% human serum (Sigma-Aldrich, #H4522-100ML) and 500 U/ml recombinant IL-2 (PeproTech, #20002-50UG) at 37 °C and 5% CO2. Primary NK cells were washed twice with PBS and suspended at 5–10 × 107 cells/

(7) Estrogen Induced Regulation of Mucosal‐Associated Invariant T Cells in AsthmaJournal of Immunology ResearchMarch 20, 2026Shubhanshi Trivedi, Samuel E. Aamodt, Thomas P. Huecksteadt, Elizabeth J. Myers, Grace Helen McGee, Jackson G. Cacioppo, Jeffrey Aubé, Robert Paine, Daniel T. Leung, Kristi J. WarrenFisher, MA) at 37°C 5% CO2 for 4−5 days in the presence of survival cytokines; human IL‐2 (10 ng/mL; cat# 200‐02‐50UG, Thermo Fisher, MA) and IL‐7 (10 ng/mL; Cat# BT‐007‐010, Bio‐techne, R&D Systems Inc., MN). To model

(8) Durvalumab and cediranib with and without olaparib in recurrent ovarian cancer: a phase II proof-of-concept studyNature CommunicationsMarch 16, 2026Junya Tabata, Tzu-Ting Huang, Elena Giudice, Kristen R. Ibanez, Jayakumar R. Nair, Aanika Balaji Warner, Britanny B. Solarz, Valentina Bolanos, Bernadette Redd, Nahoko Sato, et al.VA, USA), and cultured in RPMI-1640 supplemented with 10% FBS and recombinant human IL-2 (50 IU/mL, #200-02-50UG, Thermo Fisher Scientific, Rockville, MD, USA). Cell density was adjusted to 1 × 106 cells/mL, and the

(9) A 3D multi-compartment assembloid to study combined immune cell infiltration and cytotoxicityCell Reports MethodsFebruary 23, 2026Eban A. Hanna, Ashleigh J. Crawford, Wenxuan Du, Adrian Johnston, David Schell, Zeqi Wan, Ting-Hsi Chen, Fan Wu, Kehan Ren, Yeongseo Lim, et al.resuspended in a 1:1 (v/v) ratio of complete X-Vivo supplemented (Lonza 02-060Q) with 100 U/mL of IL2 (Thermo 200-02-50UG) to RECON buffer (1.1 g sodium bicarbonate (Sigma S5761) and 2.4 g HEPES (Acros organics CAS 7365-45-9)

(10) Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T cells Antitumor Immunity Through Metabolic ReprogrammingCancer Immunology ResearchFebruary 20, 2026Phaethon Philbrook, Matthew J. Dean, Maria Dulfary Sanchez-Pino, Li Qin Zheng, Jovanny Zabaleta, Julio A. Vázquez-Martínez, Darwin Chang, Jessica K. Mandula, Timothy I. Shaw, Dorota Wyczechowska, et al.harvested, counted, and replated in fresh cRPMI, 0.5μg/ml plate-bound anti-CD3/28, and 10ng/ml IL-2 (Thermo #200–02-50UG). This process was repeated every 48 h for a total culture duration of six days prior to use. Human

(11) Medium-Chain Fatty Acid Receptor GPR84 Modulates Cytotoxic CD8 T-cell Antitumor Immunity through Metabolic ReprogrammingCancer Immunol ResJanuary 20, 2026Phaethon Philbrook, Matthew J. Dean, Maria Dulfary Sanchez-Pino, Li Qin Zheng, Jovanny Zabaleta, Julio A. Vázquez-Martínez, Darwin Chang, Jessica K. Mandula, Timothy I. Shaw, Dorota Wyczechowska, et al.replated in fresh cRPMI, 0.5 μg/mL plate-bound anti-CD3/28, and 10 ng/mL IL2 (Thermo Fisher Scientific #200-02-50UG). This process was repeated every 48 hours for a total culture duration of 6 days prior to use. Human

(12) Characterization of a pathogenic subpopulation of human glioma associated macrophages linked to glioma progressionCancer CellJanuary 12, 2026Kenny Kwok Hei Hei Yu, Zaki Abou-Mrad, Kristof Törkenczy, Isabell Schulze, Jennifer Gantchev, Gerard Baquer, Kelsey Hopland, Evan D. Bander, Umberto Tosi, Cameron Brennan, et al.Solution (1000X),Invitrogen,cat# 00-4505-51 "Human IL-2 Recombinant Protein, PeproTech®",Gibco,cat# 200-02-50UG "Human IL-15 Recombinant Protein, PeproTech®",Gibco,cat# 200-15-10UG Critical commercial assays,Critical

(13) MMP11 promotes immune escape in esophageal carcinoma cells via the PD-L1/c-Myc signaling pathwayTranslational OncologyJanuary 1, 2026Shixing Li, Xuelei Lou, Zukuan Chang, Jinzhan Liu, Huilin Lu106 per well to the lower chamber (ESCA cells: Tregs = 1 : 2). Interleukin (IL)-2 (20 ng/mL, cat. no 200–02–50UG; Gibco; Thermo Fisher Scientific, Inc.), CD3/CD28 T Cell Activator (cat. no 11131D; Invitrogen; Thermo

(14) Actin waves guide an outward movement of microclusters in the lymphocyte immunological synapseEMBO ReportsDecember 22, 2025Aheria Dey, Samuel Z Khiangte, Srishti Mandal, Huw Colin-York, Marco Fritzsche, Sumantra Sarkar, Sudha KumariHematopoietic Cell Medium,Lonza,Catalog #: BEBP02-055Q Human IL-2 Recombinant Protein,PeproTech,Catalog # 200-02-50UG HEPES,Gbioscience,Catalog #:RC-060 6X His-ICAM1,Thermo Fisher,Catalog #10346H03H50 NaCl,Merck(Emparta),CAS

(15) HIV-induced sialoglycans on infected CD4+ T cells promote immune evasion from myeloid cell-mediated killingNat CommunDecember 13, 2025Shalini Singh, S. M. Shamsul Islam, Rui Liu, Opeyemi S. Adeniji, Lacy M. Simons, Pratima Saini, Hiroaki Tateno, Ali Danesh, Paul W. Denton, Leila B. Giron, et al.cultured using the same medium supplemented with 30 U/ml recombinant human IL-2 (PeproTech, Catalog #200-02-50UG). Primary monocyte-derived macrophages (MDMs) were differentiated for 7-8 days, as described previously14,70.

(16) CD9 antibody enhances the anti-leukemia efficacy of γδT cells in adult B cell acute lymphoblastic leukemiaiScienceNovember 21, 2025Yan Huang, Jingjing Wen, Luting Luo, Chenxing Zhao, Shaozhen Chen, Jiajie Yang, Wanying Liu, Changjian Yan, Yi Chen, Zhengjun Wu, et al.ImmunoCult Human CD3/CD28 T Cell Activator,STEMCELL Technologies,Cat#10971 Recombinant human IL-2 (hIL-2),Thermo Fisher Scientific,Cat#200-02-50UG Recombinant human IL-15 (hIL-15),Thermo Fisher Scientific,Cat#200-15-10UG Penicillin-Streptomycin

(17) ER stress induced mitochondrial dysfunction drives Treg instability in coronary artery diseaseEMBO Molecular MedicineOctober 21, 2025Smriti Parashar, Mohammad Oliaeimotlagh, Payel Roy, Qingkang Lyu, Anusha Bellapu, Mikhail Fomin, Sunil Kumar, Yan Wang, Chantel C McSkimming, Coleen A McNamara, et al.PeproTech®",ThermoFisher,Cat.#300-02-20UG "Human IL-2 Recombinant Protein, PeproTech®",ThermoFisher,Cat.#200-02-50UG "Amersham™ Protran® Western blotting membranes, nitrocellulose",Amersham,Cat.#GE10600001 Bovine serum

(18) Combining Microwave Ablation With CAR-T-Cell Therapy in Tumor-Bearing Mouse ModelsBIO-PROTOCOLOctober 20, 2025Bihui Cao, Gabrielle L. Wheeler, Jensen Mast, Qi Zhao, Jia Shenserum (FBS) (Gibco, catalog number: A5670701) 9. Human recombinant IL-2 (PeproTech, catalog number: 200-02-50UG) 10. Penicillin-streptomycin (Gibco, catalog number:15140122) 11. Povidone iodine (Sigma-Aldrich, catalog

(19) Combining Microwave Ablation With CAR-T-Cell Therapy in Tumor-Bearing Mouse ModelsBio ProtocOctober 20, 2025Bihui Cao, Gabrielle L. Wheeler, Jensen Mast, Qi Zhao, Jia Shenserum (FBS) (Gibco, catalog number: A5670701) 9. Human recombinant IL-2 (PeproTech, catalog number: 200-02-50UG) 10. Penicillin-streptomycin (Gibco, catalog number:15140122) 11. Povidone iodine (Sigma-Aldrich, catalog

(20) Phase II proof-of-concept study of durvalumab and cediranib with and without olaparib in recurrent ovarian cancerResearch SquareOctober 5, 2025Jung-Min Lee, Junya Tabata, Tzu-Ting Huang, Elena Giudice, Kristen Ibanez, Jayakumar Nair, Aanika Warner, Britanny Solarz, Valentina Bolanos, Bernadette Redd, et al.were thawed and cultured in RPMI-1640 supplemented with 10% FBS and recombinant human IL-2 (50 IU/mL, 200-02-50UG, ThermoFisher Scientific, Rockville, MD, USA). Cell density was adjusted to 1 × 106 cells/mL, and the

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IL-2, PeproTech from Thermo Fisher Scientific

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IL-2, PeproTech from Thermo Fisher Scientific

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