Recombinant Human Interleukin-12 receptor subunit beta-1 (IL12RB1), partial MBS9020057 from MyBioSource.com

Description

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade

Product Specs
ItemRecombinant Human Interleukin-12 receptor subunit beta-1 (IL12RB1), partial
CompanyMyBioSource.com
Price $330.00Supplier Page View Company Product Page
Catalog NumberMBS9020057
FormatLiquid or Lyophilized powder
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8
Size0.02 mg (E-Coli)
Molecular Weight42,366 Da
PurityGreater than 85% as determined by SDS-PAGE
NCBI Full Gene Nameinterleukin 12 receptor subunit beta 1
NCBI Gene AliasesIL12RB, CD212, IMD30, IL-12R-BETA1
Domain/Region/Terminus24-545aa; Partial
Molecule NameInterleukin-12 receptor subunit beta-1 (IL12RB1)
TypeRecombinant Protein
Source/Expression SystemE Coli or Yeast or Baculovirus or Mammalian Cell

Sequence

CRTSECCFQD PPYPDADSGS ASGPRDLRCY RISSDRYECS WQYEGPTAGV SHFLRCCLSS GRCCYFAAGS ATRLQFSDQA GVSVLYTVTL WVESWARNQT EKSPEVTLQL YNSVKYEPPL GDIKVSKLAG QLRMEWETPD NQVGAEVQFR HRTPSSPWKL GDCGPQDDDT ESCLCPLEMN VAQEFQLRRR QLGSQGSSWS KWSSPVCVPP ENPPQPQVRF SVEQLGQDGR RRLTLKEQPT QLELPEGCQG LAPGTEVTYR LQLHMLSCPC KAKATRTLHL GKMPYLSGAA YNVAVISSNQ FGPGLNQTWH IPADTHTEPV ALNISVGTNG TTMYWPARAQ SMTYCIEWQP VGQDGGLATC SLTAPQDPDP AGMATYSWSR ESGAMGQEKC YYITIFASAH PEKLTLWSTV LSTYHFGGNA SAAGTPHHVS VKNHSLDSVS VDWAPSLLST CPGVLKEYVV RCRDEDSKQV SEHPVQPTET QVTLSGLRAG VAYTVQVRAD TAWLRGVWSQ PQRFSIEVQV SD

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