Description
Chemerin-9 (149-157) TFA is a potent agonist of chemokine-like receptor 1 (CMKLR1). Chemerin-9 (149-157) TFA has anti-inflammatory activity. Chemerin-9 (149-157) TFA stimulates phosphorylation of Akt and ERK as well as ROS production. Chemerin-9 (149-157In Vitro:Chemerin-9 (149-157) TFA (0.1 nM; 24 h; cardiac fibroblasts) stimulates migration in cardiac fibroblasts and stimulates phosphorylation of Akt and ERK as well as ROS production. MCE has not independently confirmed the accuracy of these methods. TheyIn Vivo:Chemerin-9 (149-157) TFA (0.2mg/kg; i.p.; daily, for 42 days) alleviates glucose intolerance and IR in PDM mice. ?\nChemerin-9 (149-157) TFA (7.7? µg /kg; i.h.; daily, for 28 days) has anti-inflammatory and anti-angiogenic effects in ApoE -/- mice aBiological Activity:Chemerin-9 (149-157) TFA is a potent agonist of chemokine-like receptor 1 (CMKLR1). Chemerin-9 (149-157) TFA has anti-inflammatory activity. Chemerin-9 (149-157) TFA stimulates phosphorylation of Akt and ERK as well as ROS production. Chemerin-9 (149-157