Description
A peptide agonist of CXCR7; selectively activates CXCR7 (EC50 = 0.61 nM) over µ-, δ-, and κ-opioid receptors and the nociceptin opioid peptide (NOP) receptor in β-arrestin recruitment assays at 3 µM; prevents dynorphin A-induced uptake of opioid peptides by CXCR7 in U87-ACKR3 cells at 3 µM