UGT1A4 Recombinant Protein (Human) (OPCA04373) from Aviva Systems Biology

Description

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1 (By similarity)

Product Specs
ItemUGT1A4 Recombinant Protein (Human) (OPCA04373)
CompanyAviva Systems Biology
Price Supplier Page View Company Product Page
Catalog NumberOPCA04373
Size25ul, 100ul
TypeProtein
Molecule NameUDP-glucuronosyltransferase 1-4
SpeciesHomo sapiens, Human
FormatIf the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0., Liquid or Lyophilized powder
PurityGreater than 90% as determined by SDS-PAGE
Gene NameUDP glucuronosyltransferase family 1 member A4
Molecular Weight61 kDa
NCBI Gene AliasesUGT1, HUG-BR2, UGT1.4, UGT-1A, UGT1A, UGT-1D, UGT1A4S, UGT1A1, UGT1-04, hUG-BR1, UGT1-01, UGT1D, UGT1.1, GNT1, UDPGT, UDPGT 1-4
Conjugate/TagN-terminal 6xHis-tagged
Source/Expression SystemE.coli

Sequence

GKVLVVPTDG SPWLSMREAL RELHARGHQA VVLTPEVNMH IKEEKFFTLT AYAVPWTQKE FDRVTLGYTQ GFFETEHLLK RYSRSMAIMN NVSLALHRCC VELLHNEALI RHLNATSFDV VLTDPVNLCG AVLAKYLSIP AVFFWRYIPC DLDFKGTQCP NPSSYIPKLL TTNSDHMTFL QRVKNMLYPL ALSYICHTFS APYASLASEL FQREVSVVDL VSYASVWLFR GDFVMDYPRP IMPNMVFIGG INCANGKPLS QEFEAYINAS GEHGIVVFSL GSMVSEIPEK KAMAIADALG KIPQTVLWRY TGTRPSNLAN NTILVKWLPQ NDLLGHPMTR AFITHAGSHG VYESICNGVP MVMMPLFGDQ MDNAKRMETK GAGVTLNVLE MTSEDLENAL KAVINDKSYK ENIMRLSSLH KDRPVEPLDL AVFWVEFVMR HKGAPHLRPA AHDLTWYQYH SLDVIGFLLA VVLTVAFITF KCCAYGYRKC LGKKGRVKKA HKSKTH

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