Tau-441 (2N4R) Wild-Type Pre-formed Fibrils SPR-480 from StressMarq Biosciences Inc

Product Specs
ItemTau-441 (2N4R) Wild-Type Pre-formed Fibrils
CompanyStressMarq Biosciences Inc
Price Supplier Page View Company Product Page
Catalog NumberSPR-480
ApplicationsWB, SDS-PAGE, In vivo assay, In vitro assay
Size100 µg
Research AreaAlzheimer's Disease, Axon Markers, Cell Markers, Cell Signaling, Cytoskeleton, Microtubules, MT Associated Proteins, Neurodegeneration, Neuron Markers, Neuroscience, Tangles & Tau
NCBI Full Gene Namemicrotubule associated protein tau
NCBI Gene AliasesTAU, Tau-PHF6, tau-40, PPND, DDPAC, FTDP-17, MTBT2, MSTD, PPP1R103, MTBT1, MAPTL
Conjugate/TagNo Tag
TypeProtein
Source/Expression SystemE. coli
Purity>95%
SpeciesHuman

Sequence

MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKESPLQT PTEDGSEEPG SETSDAKSTP TAEDVTAPLV DEGAPGKQAA AQPHTEIPEG TTAEEAGIGD TPSLEDEAAG HVTQARMVSK SKDGTGSDDK KAKGADGKTK IATPRGAAPP GQKGQANATR IPAKTPPAPK TPPSSGEPPK SGDRSGYSSP GSPGTPGSRS RTPSLPTPPT REPKKVAVVR TPPKSPSSAK SRLQTAPVPM PDLKNVKSKI GSTENLKHQP GGGKVQIINK KLDLSNVQSK CGSKDNIKHV PGGGSVQIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L

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StressMarq Biosciences Inc

117-1537 Hillside Ave.

Victoria, British Columbia V8T 4Y2

Canada

Phone: +1-250-294-9065
Fax: 1-250-294-9025

Email: info@stressmarq.com

Company Profile

Website: http://www.stressmarq.com

(1) Tau-targeting active immunotherapy slows progression and reduces pathology in mouse models of tauopathyBrain pathology (Zurich, Switzerland)May 1, 2026Brown CM, Brooks JK, Kelly L, Vroom MM, Longo M, Dodart JC, Carare R, Boyd JD.

(2) A novel lncRNA FAM151B-DT regulates degradation of aggregation prone proteinsMolecular psychiatryDecember 1, 2025Renganathan A, Minaya MA, Broder M, Alfradique-Dunham I, Miller RL, Dhavale DD, Moritz M, Bhagat R, Marsh J, Verbeck A, et al.

(3) The G2019S LRRK2 mutation exacerbates α-synuclein and tau neuropathology through divergent pathways in Parkinson's disease modelsActa neuropathologicaNovember 11, 2025Tsafaras G, Cabezudo D, Wetzels L, Tsakogias I, Abey A, Bentea E, Sanchiz-Calvo M, Van den Haute C, Wade-Martins R, Baekelandt V.

(4) Seed structure and phosphorylation in the fuzzy coat impact tau seeding competencyNature communicationsOctober 17, 2025Kasen A, Lövestam S, Breton L, Meyerdirk L, McPhail JA, Piche K, Louwrier A, Capan CD, Lee H, Scheres SHW, et al.We first assessed the seeding capacity of heparin-induced wildtype tau 2N4R fibrils (StressMarq Cat# SPR-480) or RNA-induced P301S tau 2N4R fibrils (StressMarq Cat# SPR-463). As a positive control, we extracted

(5) Strain-Distinct α-Synuclein and Tau Cross-Seeding Uncovered by Correlative Approach with Optical Photothermal Infrared Sub-Micron ImagingJournal of the American Chemical SocietyAugust 6, 2025Zhan X, Li W, Hatterer E, Courade JP, Piché K, Klementieva O, Li JY.British Columbia), specifically, αSyn monomer (SPR-321), αSyn (SPR-322), Tau 0N3R (SPR-491), Tau 2N4R (SPR-480), αS&Tau3R (SPR-494), and αS&Tau4R (SPR-495). The detailed protocol for the preparation of PFFs is available

(6) Parkinson disease-associated toxic exposures selectively up-regulate vesicular glutamate transporter vGlut2 in a model of human cortical neuronsMolecular biology of the cellFebruary 1, 2025Clark KA, White AJ, Paslawski W, Alexander KD, Peng S, Young-Pearse TL, Svenningsson P, Selkoe DJ, Ho GPH.solution was mixed, aliquoted, and stored at −80°C until use. PFF treatment TTR (SPR-464) and Tau (SPR-480) PFFs were purchased from StressMarq Biosciences. αS PFFs were either purchased from StressMarq (SPR-322)

(7) Temperature-Dependent Aggregation of Tau Protein Is Attenuated by Native PLGA Nanoparticles Under in vitro ConditionsInternational journal of nanomedicineJanuary 1, 2025Paul PS, Rathnam M, Khalili A, Cortez LM, Srinivasan M, Planel E, Cho JY, Wille H, Sim VL, Mok SA, et al.

(8) ApoE4 expression disrupts tau uptake, trafficking, and clearance in astrocytesGliaJanuary 1, 2024Eisenbaum M, Pearson A, Ortiz C, Mullan M, Crawford F, Ojo J, Bachmeier C.

(9) α-Synuclein-dependent increases in PIP5K1γ drive inositol signaling to promote neurotoxicityCell reportsOctober 31, 2023Horvath JD, Casas M, Kutchukian C, Sánchez SC, Pergande MR, Cologna SM, Simó S, Dixon RE, Dickson EJ.

(10) BAG3 regulates the specificity of the recognition of specific MAPT species by NBR1 and SQSTM1bioRxiv : the preprint server for biologyFebruary 9, 2023Lin H, Sandkuhler S, Dunlea C, King DH, Johnson GVW.fibrils, the immobilized FLAG-NBR1 is incubated with 5 μg MAPT pre-formed fibrils (StressMarq Biosciences, SPR-480) and 1 μg GST or GST-BAG3 (Abnova) in the BAG buffer for 2 hours. The precipitated sample were eluted

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Tau-441 (2N4R) Wild-Type Pre-formed Fibrils

Tau-441 (2N4R) Wild-Type Pre-formed Fibrils

Tau-441 (2N4R) Wild-Type Pre-formed Fibrils

Tau-441 (2N4R) Wild-Type Pre-formed Fibrils from StressMarq Biosciences Inc

Description

Sequence

StressMarq Biosciences Inc

Citations (10)

Reviews

Tau-441 (2N4R) Wild-Type Pre-formed Fibrils from StressMarq Biosciences Inc

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