Human Flt-3 Ligand (FLT3L) Recombinant Protein PHC9414 from Thermo Fisher Scientific

Product Specs
ItemHuman Flt-3 Ligand (FLT3L) Recombinant Protein
CompanyThermo Fisher Scientific
Price Supplier Page View Company Product Page
Catalog NumberPHC9414
Regulatory StatusFor Research Use Only. Not for use in diagnostic procedures
Size10 µg
ApplicationsCELL CULTURE

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Thermo Fisher Scientific

168 Third Avenue

Waltham, MA 02451

United States

Phone: 800-678-5599

Company Profile

Website: www.thermofisher.com

(1) Generation of an induced pluripotent stem cell line from a patient with Loeys–Dietz syndromeStem Cell ResearchAugust 1, 2026Lu Liu, Amit Manhas, Chikage Noishiki, David Wu, Dipti Tripathi, Naima Turbes, Karim Sallam, Jason T. Lee, Nazish Sayedng/mL stem cell factor (SCF; PeproTech, #300–07), 100 ng/mL Flt3 ligand (Thermo Fisher Scientific, #PHC9414), 20 ng/mL interleukin-3 (IL-3; PeproTech, #200–03), 20 ng/mL erythropoietin (EPO; Thermo Fisher Scientific,

(2) Generation of two induced pluripotent stem cell lines from hypertrophic cardiomyopathy patients carrying MYBPC3 mutationsStem Cell ResearchAugust 1, 2026Catherine A. Wu, Matthew A. Wu, Shane R. Zhao, Junyi Sun, Amira G. Flores-Banuelos, Parker Walther, Matthew Wheeler, Nazish Sayed(ThermoFisher Scientific, Cat #10639011) supplemented with 100 ng/mL FLT3 (ThermoFisher Scientific, Cat #PHC9414), 100 ng/mL SCF (Peprotech, Cat #300–07), 20 ng/mL IL-6 (ThermoFisher Scientific, Cat #PHC0063), 20

(3) Generation and characterization of two human induced pluripotent stem cell lines from myotonic dystrophy type 1 patientsStem Cell ResearchAugust 1, 2026Pooja Darji, Wenqiang Liu, Wenshu Zeng, Jade T. Chao, Paul D. Pang, Matthew T. Wheeler, Marco Perez, Joseph C. Wu(ThermoFisher #10639011) supplemented with SCF (100 ng/mL, Peprotech #300–07), FLT3 (100 ng/mL, ThermoFisher #PHC9414), IL-3 (20 ng/mL, Peprotech #200–3), IL-6 (20 ng/mL, ThermoFisher #PHC0063), and EPO (20 ng/mL, ThermoFisher

(4) Generation of two induced pluripotent stem cell lines from patients carrying heterozygous PTEN mutations associated with PTEN Hamartoma Tumor SyndromeStem Cell ResearchAugust 1, 2026Kristina Zdantsevich, Renke Tan, Dong Li, Parker Walther, Uri Ladabaum, Joseph C. WuCat #10639011) and maintained for one week with hematopoietic cytokines: FLT3 ligand (100 ng/mL; Cat #PHC9414), stem cell factor (100 ng/mL; Peprotech, Cat #300–07), interleukin-6 (20 ng/mL; Cat #PHC0063), interleukin-3

(5) MLC1 alteration in human iPSCs give rise to disease-like cellular vacuolation phenotype in the astrocyte lineageOrphanet Journal of Rare DiseasesMarch 26, 2026Saumya Sharma, Vishal Bharti, Prosad Kumar Das, Abdul Rahman, Harshita Sharma, Riya Rauthan, Madhumita RC, Neerja Gupta, Rashmi Shukla, Sujata Mohanty, et al.(2 mM)] with cytokines [FLT3 (Feline McDonough Sarcoma- like tyrosine kinase 3; 100 ng/ml; Cat. No.: PHC9415), SCF (Stem cell factor;100 ng/ml; Cat. No.: PHC2116), IL-3 (Interleukin-3; 20 ng/ml; Cat. No.: PHC0034),

(6) Generation of induced pluripotent stem cell lines from patients with Emery-Dreifuss muscular dystrophyStem Cell ResearchMarch 1, 2026Mey-Sam Chorsi, Byron J.W.H. Mui, Renke Tan, Haley M. Fernandez, Lingyun Xu, Jade T. Chao, Jacinda B. Sampson, Matthew T. Wheeler, Joseph C. Wusupplemented with 100 ng/mL SCF (Peprotech, Cat #300-07), 100 ng/mL FLT3 (ThermoFisher Scientific, Cat #PHC9414), 20 ng/mL IL-3 (Peprotech, Cat #200-3), 20 ng/mL IL-6 (ThermoFisher Scientific, Cat #PHC0063), and

(7) KCNA2 variants cause dilated cardiomyopathy, obesity and sleep apnea through RAC-ERK pathwayEMBO Molecular MedicineFebruary 24, 2026Prasanth Chimata, Sahil Lall, Tarmo Annilo, M K Mathew, Andres Metspalu, Jayaprakash Shenthar, Perundurai S DhandapanySCF at 100 ng/mL (Thermo Fisher Scientific, PHC2115), FLT-3 at 100 ng/mL (Thermo Fisher Scientific, PHC9414), IL-3 at 20 ng/mL (Thermo Fisher Scientific, PHC0034), and IL-6 at 20 ng/mL (Thermo Fisher Scientific,

(8) Lymphotropic Virotherapy Induces DC and High Endothelial Venule Inflammation, Promoting the Antitumor Efficacy of Intratumor Virus AdministrationCancer Immunology ResearchFebruary 3, 2026Andrea L. Ludwig, Zachary P. McKay, Griffin P. Carter, Mark A. Katz, Georgia Howell, Vaibhav Jain, Stephanie Arvai, Dirk P. Dittmer, Darell D. Bigner, David M. Ashley, et al.cells/ml in RPMI (Gibco #11875093) + 10% FBS containing 300ng/ml human recombinant FLT3L (Thermo-Fisher #PHC9411) for 9 days. The non-adherent cells were treated with PVSRIPO or mock (24h), labeled with Celltrace

(9) Lymphotropic Virotherapy Induces DC and High Endothelial Venule Inflammation, Promoting the Antitumor Efficacy of Intratumor Virus AdministrationCancer immunology researchFebruary 3, 2026Ludwig AL, McKay ZP, Carter GP, Katz MA, Howell G, Jain V, Arvai S, Dittmer DP, Bigner DD, Ashley DM, et al.cells/ml in RPMI (Gibco #11875093) + 10% FBS containing 300ng/ml human recombinant FLT3L (Thermo-Fisher #PHC9411) for 9 days. The non-adherent cells were treated with PVSRIPO or mock (24h), labeled with Celltrace

(10) Generation of an induced pluripotent stem cell line from a patient with Varicose veinsStem cell researchDecember 1, 2025Noishiki C, Manhas A, Adkar SS, Tripathi D, Wu D, Sadat S, Liu L, Sallam K, Leeper NJ, Fukaya E, et al.medium supplemented with 100 ng/mL SCF (Peprotech, #300–07), 100 ng/mL FLT3 (Thermo Fisher Scientific, #PHC9414), 20 ng/mL IL-3 (Peprotech, #200–3), 20 ng/mL IL-6 (Thermo Fisher Scientific, #PHC0063), and 20 ng/mL

(11) Selective AMPKβ1 activation induces fetal hemoglobin in human erythroid cells and sickle cell mice via the noncanonical NRF2 pathwayScience advancesNovember 21, 2025Hara Y, Lemgart VT, Lessard S, Mercadante CJ, Ribeil JA, Hicks A, Rimmele P, Light DR.ng/ml; Thermo Fisher Scientific, #PHC9513), and Recombinant Human Flt-3 Ligand (100 ng/ml; Gibco, #PHC9411). Then, cells were differentiated into erythroid cells using a three-phase liquid culture system that

(12) Generation of induced pluripotent stem cell lines from patients with thoracic aortic aneurysm carrying the ACTA2 gene mutationStem Cell ResearchOctober 1, 2025Tian-Ding Liu, Shuai Sun, Lu Ren, Yan Zhuge, Souhrid Mukherjee, David H. Liang, Joseph C. Wu(141190144), and subsequently maintained in StemPro-34 SFM medium (10639011) enriched with 100 ng/mL FLT3 (PHC9414), 20 ng/mL IL-6 (PHC0063), 20 ng/mL EPO (PHC9631; all from ThermoFisher), 100 ng/mL SCF (300–07), and

(13) Generation of two induced pluripotent stem cell lines from dilated cardiomyopathy patients harbouring TTN mutationsStem Cell ResearchOctober 1, 2025Renke Tan, Yi-Ing Chen, Yanjun Zha, Todd Herron, Francois Haddad, Karim Sallam, Joseph C. WuStemPro™-34 SFM (Cat #10639011, Thermo Fisher Scientific) supplemented with 100 ng/mL FLT3 ligand (Cat #PHC9414, Thermo Fisher Scientific), 100 ng/mL stem cell factor (Cat #300–07, Peprotech), 20 ng/mL interleukin-6

(14) Generation of an induced pluripotent stem cell line from a malignant melanoma patient who developed the immune checkpoint inhibitor-related myasthenia gravis, myositis, and myocarditis overlap syndromeStem Cell ResearchSeptember 1, 2025Diem Thi Ngoc Huynh, Chikage Noishiki, Jacquelyn Lai, Pourya Yarahmadi, Thao Le, Dipti Tripathi, Ines Ross Tacco, Amit Manhas, Karim Sallam, Ian Y. Chen, et al.ThermoFisher Scientific) containing supplements: SCF (100 ng/mL, #300-07, Peprotech), FLT3 (100 ng/mL, #PHC9414, ThermoFisher Scientific), IL-3 (20 ng/mL, #200-3, Peprotech), IL-6 (20 ng/mL, #PHC0063, ThermoFisher Scientific

(15) Tubulin tyrosine ligase variant perturbs microtubule tyrosination, causing hypertrophy in patient-specific and CRISPR gene-edited iPSC-cardiomyocytesJCI InsightAugust 8, 2025Pratul Kumar Jain, Susobhan Mahanty, Harshil Chittora, Veronique Henriot, Carsten Janke, Minhajuddin Sirajuddin, Perundurai S. Dhandapanythe appropriate cytokines (SCF c-kit 100 ng/mL [Invitrogen, PHC2115], FLT-3 100 ng/mL [Invitrogen, PHC9414], IL-3 20 ng/mL [Invitrogen, PHC0034], and IL-6 20 ng/mL [Invitrogen, PHC0064] at their final concentration).

(16) Generation of two induced pluripotent stem cell lines from breast cancer patients carrying BRCA1 mutationsStem cell researchAugust 1, 2025Chen YI, Caudal A, Flores-Banuelos AG, Yan CD, Park WG, Viswanathan M, Wu JC.#10639011) supplemented with 100 ng/mL SCF (Peprotech #300–07), 100 ng/mL FLT3 (Thermo Fisher Scientific #PHC9414), 20 ng/mL IL-3 (Peprotech #200–3), 20 ng/mL IL-6 (Thermo Fisher Scientific #PHC0063), and 20 ng/mL

(17) Development of a robust BH3 drug toolkit for precision medicine in hematologic malignanciesTheranosticsApril 21, 2025Valentin Jacquier, Andréa Romero, Caroline Molinaro, Ritu Somayaji, Matthieu Abouladze, Ouissem Karmous Gadacha, Sara Ovejero, Hugues de Boussac, Ludovic Gabellier, Matthew S. Davids, et al.24 h in RPMI-1640 Glutamax medium (61870044, Gibco) supplemented with human FLT-3 Ligand (50 ng/mL, PHC9414, Gibco), human SCF (50 ng/mL, PHC2116, Gibco), IL-3 (10 ng/mL, PHC0034, Gibco) and IL-6 (10 ng/mL, 200-06,

(18) Generation of two induced pluripotent stem cell lines from Loeys-Dietz syndrome patients carrying heterologous mutation of TGFBR1Stem cell researchMarch 1, 2025Shang R, Sun J, Flores Banuelos AG, Zhou Y, Liang DH, Wu JC.was supplemented with 100 ng/mL SCF (Peprotech #300-07), 100 ng/mL FLT3 (Thermo Fisher Scientific #PHC9414), and 20 ng/mL each of IL-3 (Peprotech #200-3), IL-6 (Thermo Fisher Scientific #PHC0063), and EPO (Thermo Fisher Scientific

(19) Generation of induced pluripotent stem cell line from a patient with long COVIDStem Cell ResearchMarch 1, 2025David Wu, Amit Manhas, Chikage Noishiki, Dipti Tripathi, Lu Liu, Naima Turbes, Dilip Thomas, Karim Sallam, Jason T. Lee, Nazish Sayedsupplemented with specific growth factors and cytokines: 100 ng/mL FLT3 (ThermoFisher Scientific, #PHC9414), 100 ng/mL SCF (Peprotech, #300–07), 20 ng/mL IL-3 (Peprotech, #200–3), 20 ng/mL EPO (ThermoFisher Scientific

(20) Generation of two induced pluripotent stem cell lines from patients with Li-Fraumeni Syndrome carrying TP53 mutationStem cell researchDecember 1, 2024Sun J, Ren L, Canel Rivero G, Xu L, Ladabaum U, C Wu J.a mix of supplements: 100 ng/mL SCF (Peprotech #300–07), 100 ng/mL FLT3 (Thermo Fisher Scientific #PHC9414), and 20 ng/mL each of IL-3 (Peprotech #200–3), IL-6 (Thermo Fisher Scientific #PHC0063), and EPO (Thermo Fisher Scientific

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Human Flt-3 Ligand (FLT3L) Recombinant Protein from Thermo Fisher Scientific

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Thermo Fisher Scientific

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Human Flt-3 Ligand (FLT3L) Recombinant Protein from Thermo Fisher Scientific

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